Riddle Daniel L, Dumenci Levent
Departments of Physical Therapy, Orthopaedic Surgery and Rheumatology, Virginia Commonwealth University, Richmond, VA, USA.
Department of Epidemiology and Biostatistics, 1301 Cecil B. Moore, Ave., Ritter Annex, Room 939, Temple University, Philadelphia, PA, 19122, USA.
BMC Musculoskelet Disord. 2020 Sep 10;21(1):604. doi: 10.1186/s12891-020-03583-w.
A recently published paper by te Molder and colleagues in BMC Musculoskeletal Disorders confirmed prior reports indicating that definitions of good versus poor outcome cutoff scores for relevant knee arthroplasty outcomes including pain and function are heterogeneous and that this heterogeneity prevents generalizable inferences. In this Correspondence, we highlight an additional and, in our view, a more important problem with the substantial literature on this topic. There also is high homogeneity in that all studies relied on arbitrarily defined cutoff scores to differentiate good versus poor outcome. We discuss this problem and propose a method to avoid repeating the same problem in future studies designed to group patients into those with good versus those with poor outcome following knee arthroplasty.
特·莫尔德及其同事最近在《BMC肌肉骨骼疾病》上发表的一篇论文证实了先前的报道,即包括疼痛和功能在内的相关膝关节置换术结果中,良好与不良结果临界值分数的定义存在异质性,且这种异质性阻碍了可推广的推断。在这篇通信文章中,我们强调了关于该主题的大量文献中一个额外的、且在我们看来更重要的问题。所有研究都依赖于任意定义的临界值分数来区分良好与不良结果,这也存在高度同质性。我们讨论了这个问题,并提出一种方法,以避免在未来旨在将膝关节置换术后患者分为良好与不良结果两组的研究中重复出现同样的问题。