用源自婴儿利什曼原虫的疫苗对犬进行免疫接种。
Immunization of dogs with a Leishmania infantum-derived vaccine.
作者信息
Ogunkolade B W, Vouldoukis I, Frommel D, Davoust B, Rhodes-Feuillette A, Monjour L
机构信息
Department of Tropical Medicine, Pitié-Salpétrière School of Medicine, Paris, France.
出版信息
Vet Parasitol. 1988 Apr;28(1-2):33-41. doi: 10.1016/0304-4017(88)90016-7.
PMID:3291382
Abstract
A partially-purified extract of Leishmania infantum has been administered to healthy dogs. Post-immunization sera were found to neutralize the infectivity of L. infantum and to abate the development of L. major. Muramyl dipeptide and one of its derivates, murabutide, were the best adjuvants.
摘要
已将婴儿利什曼原虫的部分纯化提取物接种给健康犬。发现免疫后的血清可中和婴儿利什曼原虫的感染性，并减轻硕大利什曼原虫的发育。胞壁酰二肽及其衍生物之一，胞壁酰三肽，是最佳佐剂。
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