Department of Radiology, Patnos State Hospital, 04500, Patnos, Ağrı, Turkey.
Department of Radiology, Bursa Uludag University Faculty of Medicine, 16059, Nilüfer, Bursa, Turkey.
Neuroradiology. 2021 Mar;63(3):399-407. doi: 10.1007/s00234-020-02527-4. Epub 2020 Sep 11.
To determine the diagnostic accuracy of 3D time of flight MR angiography (TOF-MRA), contrast enhanced MR angiography (CE-MRA), and T1-weighted high-resolution isotropic volume examination (THRIVE) at 3 T for the evaluation of intracranial aneurysm occlusion after endovascular treatment and to evaluate the usability of the THRIVE sequence in endovascular treatment follow-up.
In 3 T MR follow-up examinations of 66 aneurysms in 50 patients treated endovascularly, 3D TOF-MRA (index test), THRIVE (index test), and CE-MRA (reference standard) examinations were performed in a retrospective consecutive case series. Source images were classified as class 1, class 2, and class 3 according to the Raymond criteria using MIP (maximum intensity projection) techniques. The compatibility between sequences was evaluated with the Kappa test. The sensitivity and specificity were also calculated.
In the evaluation of THRIVE and CE-MRA sequences, compatibility was determined in 61 cases in total, with an overall fit of 61/66 (92.42%). A statistically significant correlation was found between THRIVE and CE-MRA (p < 0.001, κ = 0.800). In the evaluation of TOF and CE-MRA sequences, compatibility was determined in 54 cases in total, and the overall fit was 54/66 (81.8%). A statistically significant agreement was found between TOF and CE-MRA (p < 0.001, κ = 0.502). Assuming that CE-MRA is a reference standard, the sensitivity and specificity of the TOF sequence were 44.4% and 97.9%, respectively, and the sensitivity and specificity of the THRIVE sequence were 77.8% and 97.9%, respectively.
The THRIVE sequence can be used as a noncontrast method for monitoring endovascularly treated intracranial aneurysms.
在 3T 磁共振（MR）中，评估血管内治疗后颅内动脉瘤闭塞的诊断准确性，比较三维时间飞跃磁共振血管成像（3D-TOF-MRA）、对比增强磁共振血管成像（CE-MRA）和 T1 加权高分辨率各向同性容积检查（THRIVE）的诊断效能，并探讨 THRIVE 序列在血管内治疗随访中的可用性。
对 50 例 66 个颅内动脉瘤患者的血管内治疗后 3T MR 随访检查进行回顾性连续病例系列研究。在源图像上，采用最大密度投影（MIP）技术，根据 Raymond 分级标准将 3D-TOF-MRA（受试方法）、THRIVE（受试方法）和 CE-MRA（参考标准）分为 1 类、2 类和 3 类。采用 Kappa 检验评估序列间的一致性。计算敏感度和特异度。
在 THRIVE 和 CE-MRA 序列的评估中，共确定了 61 例符合条件的病例，总符合率为 61/66（92.42%）。THRIVE 和 CE-MRA 之间存在统计学显著相关性（p<0.001，κ=0.800）。在 3D-TOF 和 CE-MRA 序列的评估中，共确定了 54 例符合条件的病例，总符合率为 54/66（81.8%）。3D-TOF 和 CE-MRA 之间具有统计学显著一致性（p<0.001，κ=0.502）。以 CE-MRA 为参考标准，3D-TOF 序列的敏感度和特异度分别为 44.4%和 97.9%，THRIVE 序列的敏感度和特异度分别为 77.8%和 97.9%。
THRIVE 序列可作为血管内治疗颅内动脉瘤的非对比监测方法。
