Chair and Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Poland.
Eur Ann Allergy Clin Immunol. 2020 Nov;52(6):277-279. doi: 10.23822/EurAnnACI.1764-1489.170. Epub 2020 Nov 3.
Prenatal environmental factors are suggested to be implicated in the dramatic increase in Atopic Dermatitis (AD) in recent years. The aim of this study was to investigate the possible associations between pregnant woman's diet and clinical and laboratory variables of AD in offsprings. A cross-sectional study was performed in children 3-36 months of age with infantile-onset AD. Maternal dietary habits during pregnancy were evaluated in terms of the usual intake of dairy foods, eggs, red meat and poultry, fish, fruits and vegetables. One hundred pairs of mothers and their children with AD were included. A higher serum total IgE and peripheral eosinophila in children were associated with a lower maternal egg intake during pregnancy. Except for a strong trend toward significance of correlation between fish consumption and the lack of atopic multimorbidity, no relationships were revealed between clinical variables of child's AD (the age of onset of AD, its severity, atopic multimorbidity) and the mother's dietary habit. Our preliminary findings suggest that maternal egg intake during pregnancy might be a factor influencing laboratory markers of atopy in offsprings. Prospective cohort studies are needed to confirm and clarify this relationship.
产前环境因素被认为与近年来特应性皮炎（AD）的显著增加有关。本研究旨在探讨孕妇饮食与儿童 AD 的临床和实验室变量之间可能存在的关联。本研究为一项横断面研究，纳入了 3-36 月龄的婴儿期起病 AD 患儿。评估了孕妇在怀孕期间的饮食习惯，包括乳制品、鸡蛋、红肉和家禽、鱼类、水果和蔬菜的通常摄入量。共纳入 100 对 AD 患儿及其母亲。儿童的血清总 IgE 和外周嗜酸性粒细胞较高与母亲在怀孕期间摄入的鸡蛋较少有关。除了鱼类摄入与非特应性多种共病之间的相关性有较强的趋势外，儿童 AD 的临床变量（AD 的发病年龄、严重程度、特应性多种共病）与母亲的饮食习惯之间没有发现关系。我们的初步研究结果表明，孕妇在怀孕期间的鸡蛋摄入量可能是影响后代特应性实验室标志物的一个因素。需要前瞻性队列研究来证实和阐明这种关系。
