Misonou J, Natori T, Aizawa M, Jou B, Tamaki A, Ogasawara M
1st Department of Pathology, Hokkaido University School of Medicine, Japan.
Acta Pathol Jpn. 1988 Feb;38(2):225-34. doi: 10.1111/j.1440-1827.1988.tb01100.x.
A rare case of recurrent cervical cancer presenting multiple metastases to the small intestine is reported. A 69-year-old Japanese woman with a past history of early-stage (Ia) cervical cancer 13 years previously suffered sudden onset of panperitonitis caused by perforation of the small intestine. In the perforated lesion, squamous cell carcinoma, which was histologically similar to that of the primary lesion, was observed, and was diagnosed as a late recurrence of the cervical cancer. Perforation of the small intestine caused by tumor metastasis, especially metastasis from cervical cancer, rerely occurs. Furthermore, recurrence of an early cervical cancer presenting 13 years after hysterectomy is extremely rare. The present case draws attention to the possibility of late recurrence of cervical cancer, even in cases treated at the early-stage.
报告了一例罕见的复发性宫颈癌,其小肠出现多处转移。一名69岁的日本女性,13年前有早期(Ia期)宫颈癌病史,突然发生由小肠穿孔引起的全腹膜炎。在穿孔病变处,观察到组织学上与原发病变相似的鳞状细胞癌,被诊断为宫颈癌晚期复发。肿瘤转移,尤其是宫颈癌转移引起的小肠穿孔很少见。此外,子宫切除术后13年出现早期宫颈癌复发极为罕见。本病例提醒人们注意,即使是早期治疗的宫颈癌病例,也可能出现晚期复发。