Onal Cem, Nursal Gul Nihal, Torer Nurkan, Kayaselcuk Fazilet
Department of Radiation Oncology, Baskent University, Faculty of Medicine, Adana, Turkey.
Department of Nuclear Medicine, Baskent University, Faculty of Medicine, Ankara, Turkey.
Rep Pract Oncol Radiother. 2015 May-Jun;20(3):239-42. doi: 10.1016/j.rpor.2014.12.005. Epub 2015 Jan 5.
In approximately 8% of cervical carcinoma patients, gastrointestinal tract is involved, most commonly the rectosigmoid portion, because of local extension. Isolated metastases to small bowel are exceedingly rare.
We present a case of a 63-year-old woman with cervical cancer who developed isolated jejunal metastasis 8 months after postoperative chemoradiotherapy. The patient was alive with no evidence of disease 6 months after resection of metastasis. Very few cases have been reported concerning squamous cell carcinoma of the cervix with documented metastases to the small bowel. There is only one published case report of cervical cancer with multiple metastases to the small intestine and jejunum. To our knowledge, this is the first case of cervical cancer with isolated jejunal metastasis, which was initially demonstrated with positron emission tomography and confirmed histopathologically.
Although the exact mechanism underlying the isolated metastasis is unknown, hematogenous spread or tumor seeding during surgery may play a role.
在约8%的宫颈癌患者中，胃肠道会因局部侵犯而受累，最常见的是直肠乙状结肠部分。孤立性小肠转移极为罕见。
我们报告一例63岁宫颈癌女性患者，术后放化疗8个月后出现孤立性空肠转移。转移灶切除6个月后，患者存活且无疾病证据。关于宫颈鳞状细胞癌伴小肠转移的病例报道极少。仅有一篇关于宫颈癌多发转移至小肠和空肠的病例报告发表。据我们所知，这是首例经正电子发射断层扫描最初显示并经组织病理学证实的孤立性空肠转移宫颈癌病例。
尽管孤立性转移的确切机制尚不清楚，但血行播散或手术过程中的肿瘤种植可能起了作用。
