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Knee Surg Sports Traumatol Arthrosc. 2018 Mar;26(3):875-881. doi: 10.1007/s00167-016-4318-4. Epub 2016 Sep 12.
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自体基质诱导软骨生成术作为第一跖趾关节骨关节炎的手术治疗方法:即时和中期结果。

The Use of Autologous Matrix-Induced Chondrogenesis as a Surgical Treatment for Patients with the First Metatarsophalangeal Joint Osteoarthritis: Immediate and Medium-Term Results.

机构信息

V.A. Nasonova Research Institute of Rheumatology, Moscow, Russian Federation.

出版信息

Cartilage. 2021 Dec;13(1_suppl):1354S-1365S. doi: 10.1177/1947603520958127. Epub 2020 Sep 11.

DOI:10.1177/1947603520958127
PMID:32917097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8808820/
Abstract

AIM

To demonstrate the immediate and medium-term results of the surgical treatment of patients with first metatarsophalangeal (MTP) joint osteoarthritis (OA) using the autologous matrix-induced chondrogenesis (AMIC) technique and to evaluate the effectiveness.

MATERIALS AND METHODS

Preoperatively the range of motion (ROM) in the first MTP joint was determined, and the following questionnaires were used: Visual Analogue Scale (VAS) of pain, American Orthopedic Foot & Ankle Society (AOFAS) score, and Functional Foot Index (FFI). All of the patients experienced a significant restriction of the ROM in the first MTP joint. The VAS of pain median was 70, AOFAS 52, and FFI 5.8.

RESULTS

AMIC was performed in 19 patients with first MTP joint OA. All the patients experienced a significant restriction of ROM in the first MTP joint. The VAS of pain median was 70, AOFAS 52, and FFI 5.8. By the third month, VAS of pain decreased to 25, FFI to 2.2; AOFAS median increased to 77, ROM to 60°. Six months after the surgery VAS of pain decreased to 10, FFI to 1.1; AOFAS median increased to 90, ROM to 65°. After a year of observation, VAS of pain decreased to 5, FFI to 1,0; AOFAS median increased to 92.5, ROM to 71.5°.

CONCLUSION

The results showed that a first MTP joint AMIC procedure can be a fairly effective method of surgical treatment that can relieve pain and significantly improve the quality of life of patients with first MTP joint OA.

摘要

目的

展示使用自体诱导软骨形成(AMIC)技术治疗第一跖趾关节(MTP)骨关节炎(OA)患者的即刻和中期结果,并评估其疗效。

材料和方法

术前确定第一 MTP 关节的活动范围(ROM),并使用以下问卷进行评估:疼痛视觉模拟量表(VAS)、美国矫形足踝协会(AOFAS)评分和足部功能指数(FFI)。所有患者均经历第一 MTP 关节 ROM 明显受限。疼痛 VAS 中位数为 70,AOFAS 为 52,FFI 为 5.8。

结果

19 例第一 MTP 关节 OA 患者行 AMIC 治疗。所有患者均经历第一 MTP 关节 ROM 明显受限。疼痛 VAS 中位数为 70,AOFAS 为 52,FFI 为 5.8。术后第 3 个月,疼痛 VAS 降至 25,FFI 降至 2.2;AOFAS 中位数增至 77,ROM 增至 60°。术后 6 个月,疼痛 VAS 降至 10,FFI 降至 1.1;AOFAS 中位数增至 90,ROM 增至 65°。术后 1 年观察时,疼痛 VAS 降至 5,FFI 降至 1.0;AOFAS 中位数增至 92.5,ROM 增至 71.5°。

结论

结果表明,第一 MTP 关节 AMIC 手术是一种相当有效的治疗方法,可缓解疼痛,显著提高第一 MTP 关节 OA 患者的生活质量。