Graduate Program in Biomedical Gerontology, School of Medicine, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Postgraduate Program in Gerontology, Federal University of Santa Maria (UFSM), Santa Maria, Brazil; Department of Food and Nutrition, Federal University of Santa Maria (UFSM), Palmeira das Missões, Brazil.
Nutrition. 2020 Nov-Dec;79-80:110955. doi: 10.1016/j.nut.2020.110955. Epub 2020 Jul 24.
The aim of this study was to verify the accuracy of the SARC-F and the SARC-CalF as screening tools for sarcopenia in community-dwelling older women ≥60 y of age.
This was a cross-sectional study evaluating a convenience sample of women ≥60 y of age, living in Southern Brazil. Sarcopenia was defined according to the criteria proposed in the latest European Working Group on Sarcopenia in Older People consensus (EWGSOP2). Appendicular muscle mass was assessed by dual-energy x-ray absorptiometry. Muscle strength was measured by handheld dynamometry, and physical performance through the 4-m gait speed test. The SARC-F questionnaire and SARC-CalF score for sarcopenia screening were also applied.
We evaluated 288 participants, with a mean age of 67.6 ± 5.8 y. The frequency of probable and confirmed sarcopenia in the sample was 7.3% and 2.1%, respectively. The frequency of risk for sarcopenia assessed by the SARC-F was 4.5% and SARC-CalF 22.2%. Despite the excellent specificity (95.4%) demonstrated by the SARC-F, its sensitivity in identifying confirmed cases was null, whereas the SARC-CalF showed high sensitivity (83.3%) and good specificity (79%).
The present study findings suggested that SARC-CalF may be able to outperform SARC-F as a sarcopenia screening tool in women ≥60 y of age even under the new EWGSOP2 criteria, the main determinant of which is strength as observed in studies based on the previous definition.
本研究旨在验证 SARC-F 和 SARC-CalF 作为 60 岁及以上社区居住的老年女性肌少症筛查工具的准确性。
这是一项横断面研究,评估了居住在巴西南部的 60 岁及以上的女性的便利样本。肌少症根据欧洲老年人肌少症工作组(EWGSOP2)最新共识提出的标准定义。四肢骨骼肌质量通过双能 X 射线吸收法评估。肌肉力量通过手持测力计测量,身体机能通过 4 米步行速度测试。还应用了 SARC-F 问卷和 SARC-CalF 评分进行肌少症筛查。
我们评估了 288 名参与者,平均年龄为 67.6 ± 5.8 岁。样本中可能和确诊肌少症的频率分别为 7.3%和 2.1%。SARC-F 评估的肌少症风险频率为 4.5%,SARC-CalF 为 22.2%。尽管 SARC-F 表现出极好的特异性(95.4%),但其对确诊病例的敏感性为零,而 SARC-CalF 则表现出较高的敏感性(83.3%)和良好的特异性(79%)。
本研究结果表明,即使在新的 EWGSOP2 标准下,SARC-CalF 可能比 SARC-F 更能作为 60 岁及以上女性的肌少症筛查工具,其主要决定因素是力量,这与基于之前定义的研究一致。