Department of Biomedical Science and Technology, College of Medicine, East-West Medical Research Institute, Kyung Hee University, Seoul, Republic of Korea.
Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
J Am Med Dir Assoc. 2020 Jun;21(6):752-758. doi: 10.1016/j.jamda.2020.03.018. Epub 2020 May 5.
To describe the prevalence of sarcopenia in a large group of community-dwelling older adults using the Asian Working Group for Sarcopenia (AWGS) 2019 definition and algorithm.
Cross-sectional data analysis of a cohort study.
The Nationwide Korean Frailty and Aging Cohort Study (KFACS).
A total of 2123 ambulatory community-dwelling older adults, aged 70 to 84 years (mean, 75.9 ± 3.9 years; 49.5% women) were enrolled in the KFACS.
Appendicular skeletal muscle mass was measured by dual-energy x-ray absorptiometry. Physical function was assessed by handgrip strength, usual gait speed, the 5-times-sit-to-stand test, the timed up-and-go test, and the Short Physical Performance Battery. In a case-finding assessment, screening for sarcopenia was performed using the calf circumference (CC), SARC-F questionnaire, and SARC-F combined with CC (SARC-CalF).
According to the AWGS 2019 algorithm, 43.5%, 7.5%, and 26.0% of the subjects in the whole study sample were classified as those at risk for sarcopenia according to CC, SARC-F, and SARC-CalF, respectively. The prevalence rates of possible sarcopenia using 3 screening tools for case-finding and muscle strength or physical performance tests according to the AWGS 2019 diagnostic algorithm were 20.1% in men and 29.2% in women. The prevalence rates of sarcopenia, when defined as low muscle mass plus low handgrip strength and/or slow gait speed, were significantly higher according to the AWGS 2019 (21.3% in men and 13.8% in women) than the AWGS 2014 (10.3% in men and 8.1% in women) definitions. The prevalence of severe sarcopenia was 6.4% in men and 3.2% in women.
CONCLUSIONS/IMPLICATIONS: The results of our study suggest that the use of CC and SARC-CalF to screen for possible sarcopenia may be more suited than using the SARC-F questionnaire alone according to the AWGS 2019 diagnostic algorithm in community-dwelling adults aged 70 to 84 years. The prevalence of sarcopenia was significantly higher according to the AWGS 2019 than AWGS 2014 criteria.
使用亚洲肌肉减少症工作组（AWGS） 2019 定义和算法，描述大量社区居住的老年人中肌少症的流行情况。
队列研究的横断面数据分析。
全国韩国虚弱和衰老队列研究（KFACS）。
共纳入 2123 名 70 至 84 岁（平均年龄 75.9 ± 3.9 岁；49.5%为女性）的社区活动老年人。
通过双能 X 射线吸收法测量四肢骨骼肌质量。通过握力、常规步行速度、5 次坐站测试、计时起立行走测试和简易体能状况量表评估身体功能。在病例发现评估中，使用小腿围（CC）、SARC-F 问卷和 SARC-F 联合 CC（SARC-CalF）筛查肌少症。
根据 AWGS 2019 算法，整个研究样本中，根据 CC、SARC-F 和 SARC-CalF，分别有 43.5%、7.5%和 26.0%的受试者被归类为有肌少症风险。使用 3 种病例发现筛查工具和根据 AWGS 2019 诊断算法的肌肉力量或身体表现测试，可能肌少症的患病率在男性中为 20.1%，在女性中为 29.2%。根据 AWGS 2019（男性 21.3%，女性 13.8%）定义，低肌肉量加低握力和/或慢步行速度的肌少症患病率明显高于 AWGS 2014（男性 10.3%，女性 8.1%）定义。严重肌少症的患病率为男性 6.4%，女性 3.2%。
结论/意义：本研究结果表明，根据 AWGS 2019 诊断算法，与单独使用 SARC-F 问卷相比，使用 CC 和 SARC-CalF 筛查可能的肌少症可能更适合 70 至 84 岁社区居住的成年人。根据 AWGS 2019，肌少症的患病率明显高于 AWGS 2014 标准。
