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Pyridoxal isonicotinoyl hydrazone (PIH): a promising new iron chelator.

作者信息

Webb J, Vitolo M L

机构信息

School of Mathematical and Physical Sciences, Murdoch University, Perth, Western Australia.

出版信息

Birth Defects Orig Artic Ser. 1988;23(5B):63-70.

PMID:3291971
Abstract
摘要

相似文献

1
Pyridoxal isonicotinoyl hydrazone (PIH): a promising new iron chelator.吡啶醛异烟酰腙（PIH）：一种有前景的新型铁螯合剂。
Birth Defects Orig Artic Ser. 1988;23(5B):63-70.
2
Chemical studies of pyridoxal isonicotinoyl hydrazone relevant to its clinical evaluation.
Birth Defects Orig Artic Ser. 1988;23(5B):71-9.
3
Pyridoxal isonicotinoyl hydrazone and its analogues.
Adv Exp Med Biol. 2002;509:205-29. doi: 10.1007/978-1-4615-0593-8_11.
4
Mechanism of in vivo iron chelation by pyridoxal isonicotinoyl hydrazone and other imino derivatives of pyridoxal.吡哆醛异烟酰腙及其他吡哆醛亚氨基衍生物的体内铁螯合机制
J Lab Clin Med. 1981 Jul;98(1):99-108.
5
Effect of pyridoxal isonicotinoyl hydrazone and analogs on iron metabolism in hepatocytes and macrophages in culture.
Birth Defects Orig Artic Ser. 1988;23(5B):81-8.
6
The iron metabolism of the human neuroblastoma cell: lack of relationship between the efficacy of iron chelation and the inhibition of DNA synthesis.人类神经母细胞瘤细胞的铁代谢：铁螯合功效与DNA合成抑制之间缺乏关联。
J Lab Clin Med. 1994 Nov;124(5):660-71.
7
Cytotoxic analogs of the iron(III) chelator pyridoxal isonicotinoyl hydrazone: effects of complexation with copper(II), gallium(III), and iron (III) on their antiproliferative activities.铁（III）螯合剂吡哆醛异烟酰腙的细胞毒性类似物：与铜（II）、镓（III）和铁（III）络合对其抗增殖活性的影响
Antimicrob Agents Chemother. 1997 Sep;41(9):2061-3. doi: 10.1128/AAC.41.9.2061.
8
Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs.氧化应激介导了吡啶醛异烟酰腙类似物的毒性。
Arch Biochem Biophys. 2004 Jan 1;421(1):1-9. doi: 10.1016/j.abb.2003.09.044.
9
Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilise iron from reticulocytes in vitro.吡啶醛异烟酰腙类铁螯合剂。去铁螯合剂的亲脂性与其在体外从网织红细胞中动员铁的能力的关系。
Can J Physiol Pharmacol. 1994 Jun;72(6):659-66. doi: 10.1139/y94-093.
10
HPLC study on stability of pyridoxal isonicotinoyl hydrazone.吡哆醛异烟酰腙稳定性的高效液相色谱研究
J Pharm Biomed Anal. 2006 Jan 23;40(1):105-12. doi: 10.1016/j.jpba.2005.06.021. Epub 2005 Aug 2.

引用本文的文献

1
Pyridoxal isonicotinoyl hydrazone (PIH) prevents copper-mediated in vitro free radical formation.吡哆醛异烟酰腙（PIH）可防止铜介导的体外自由基形成。
Mol Cell Biochem. 2001 Dec;228(1-2):73-82. doi: 10.1023/a:1013348005312.
2
Samarium-153 chelate localization in malignant melanoma.钐-153螯合物在恶性黑色素瘤中的定位
Eur J Nucl Med. 1987;13(8):432-8. doi: 10.1007/BF00292499.
3
Pyridoxal isonicotinoyl hydrazone and analogues. Study of their stability in acidic, neutral and basic aqueous solutions by ultraviolet-visible spectrophotometry.
吡哆醛异烟酰腙及其类似物。通过紫外-可见分光光度法研究它们在酸性、中性和碱性水溶液中的稳定性。
Biol Met. 1989;2(2):69-76. doi: 10.1007/BF01129203.
4
Iron chelators of the pyridoxal isonicotinoyl hydrazone class. III. Formation constants with calcium(II), magnesium(II) and zinc(II).吡啶醛异烟酰腙类铁螯合剂。III. 与钙（II）、镁（II）和锌（II）的形成常数
Biol Met. 1989;2(3):161-7. doi: 10.1007/BF01142555.