Ma Gang, Yang Rong, Gu Baochun, Wang Daofeng, Liao Wei, He Xinrong
Intensive Care Unit Department, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Ann Palliat Med. 2021 Feb;10(2):1042-1049. doi: 10.21037/apm-19-419. Epub 2020 Sep 9.
Critically ill patients with severe acute dyspnea due to malignant tracheal stenosis or tracheoesophageal fistula often need advanced respiratory support. Tracheal stenting is an important palliative treatment of such patients. This study retrospectively analyzes the efficacy and outcomes of airway stenting in patients with tracheal stenosis or tracheoesophageal fistula.
Patients underwent stenting from 2005 to 2018 in a single center were reviewed. Ninety-seven patients with malignant tracheal stenosis and/or tracheoesophageal fistula who underwent stenting were analyzed, all these patients had poor respiratory status.
The median survival time of patients after stent placement was 119 days. Forty-five patients were treated with anti-tumor therapy after placing the stent. Discharged intensive care unit (ICU) within 3 days and postoperative antitumor treatment were independent predictors for the survival time after tracheal stenting (P<0.05).
Tracheal stent implantation played an important role for additional anti-cancer treatment.
因恶性气管狭窄或气管食管瘘导致严重急性呼吸困难的重症患者通常需要高级呼吸支持。气管支架置入是此类患者的重要姑息治疗方法。本研究回顾性分析气管狭窄或气管食管瘘患者气道支架置入的疗效和结局。
回顾2005年至2018年在单一中心接受支架置入的患者。分析97例行支架置入的恶性气管狭窄和/或气管食管瘘患者,所有这些患者呼吸状况均较差。
患者支架置入后的中位生存时间为119天。45例患者在置入支架后接受了抗肿瘤治疗。3天内转出重症监护病房(ICU)及术后抗肿瘤治疗是气管支架置入后生存时间的独立预测因素(P<0.05)。
气管支架置入对辅助抗癌治疗起重要作用。