Department of Otorhinolaryngology, Head and Neck Surgery, 154454The Second Hospital of Jilin University, Changchun, Jilin, China.
Ear Nose Throat J. 2022 Jun;101(5):NP199-NP202. doi: 10.1177/0145561320956479. Epub 2020 Sep 13.
Basaloid squamous cell carcinoma and large cell neuroendocrine carcinoma are not common in head and neck, these tumors rarely occur in the larynx but both have highly aggressive clinical behavior and a high mortality rate. The diagnosis is complicated by these tumors' atypical clinical and pathological features. This case details a coexistence of basaloid squamous cell carcinoma and large cell neuroendocrine carcinoma of a woman in the larynx. The patient underwent endoscopy- and coblation-assisted transoral microsurgery to achieve hyoid horizontal epiglottidectomy and has no recurrence after 12 months of follow-up.
基底样鳞状细胞癌和大细胞神经内分泌癌在头颈部并不常见，这些肿瘤在喉部很少发生，但两者均具有高度侵袭性的临床行为和高死亡率。这些肿瘤的非典型临床和病理特征使诊断变得复杂。本病例详细介绍了一名女性喉部同时存在基底样鳞状细胞癌和大细胞神经内分泌癌的情况。患者接受了内镜和铥激光辅助的经口微创手术，行舌骨水平会厌切除术，随访 12 个月无复发。
