Rossi Nicholas A, Gietzen Rachelle, Malaya Lauren T, Haroun Kareem B, Conner Grant R, Coblens Orly, Resto Vicente A, Clement Cecilia G, Joshi Rohan
Department of Otolaryngology University of Texas Medical Branch Galveston Texas USA.
Department of Pathology University of Texas Medical Branch Galveston Texas USA.
Clin Case Rep. 2022 Jan 27;10(1):e05319. doi: 10.1002/ccr3.5319. eCollection 2022 Jan.
Combined large cell neuroendocrine carcinoma (LCNEC) and squamous cell carcinoma (SCC) of the H&N are exceptionally rare. We present the case of combined p16 negative SCC and LCNEC of the oropharynx treated with combination chemotherapy. This is the third reported case of combined neuroendocrine carcinoma and SCC of the oropharynx.
头颈部合并大细胞神经内分泌癌(LCNEC)和鳞状细胞癌(SCC)极为罕见。我们报告了一例经联合化疗治疗的口咽合并p16阴性鳞状细胞癌和大细胞神经内分泌癌的病例。这是第三例报告的口咽神经内分泌癌和鳞状细胞癌合并病例。