Aljahany Muna Saleem, Aleid Dalal Khalid, Aal Ibrahim Ahmed Mohammed
Department of Clinical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Department of Emergency Medicine, King Abdullah Bin Abdulaziz University Hospital, Riyadh, Saudi Arabia.
Am J Case Rep. 2020 Sep 14;21:e923877. doi: 10.12659/AJCR.923877.
BACKGROUND Accidental finger-stick injuries have been reported with epinephrine autoinjectors, such as EpiPen and EpiPen Jr, and can result in necrosis and digital ischemia. However, long-term adverse effects are very rare. The treatment for accidental finger-stick injuries is controversial and includes intra-arterial injections of vasodilating agents, topical vasodilators, and supportive management as needed. CASE REPORT Here, we report a case of a 26-year-old pharmacist who injected herself accidentally with an EpiPen on the tip of her index finger. Warm water and nitroglycerine gel did not alleviate her symptoms. After three hours, phentolamine was injected around the necrotic area, and the skin normalized. CONCLUSIONS All health professionals should be trained in how to handle epinephrine autoinjectors safely. Phentolamine may be efficacious in treating accidental finger-stick injuries from epinephrine autoinjectors.
据报道，使用肾上腺素自动注射器（如EpiPen和EpiPen Jr）时会发生意外手指刺伤，可导致坏死和手指缺血。然而，长期不良反应非常罕见。意外手指刺伤的治疗存在争议，包括动脉内注射血管扩张剂、局部使用血管扩张剂以及根据需要进行支持性处理。病例报告：在此，我们报告一例26岁药剂师的病例，她不小心用EpiPen注射到了食指指尖。温水和硝酸甘油凝胶未能缓解她的症状。三小时后，在坏死区域周围注射了酚妥拉明，皮肤恢复正常。结论：所有卫生专业人员都应接受如何安全处理肾上腺素自动注射器的培训。酚妥拉明可能对治疗肾上腺素自动注射器导致的意外手指刺伤有效。
