• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

术中磁共振成像辅助立体定向脑组织活检的评估：中国单中心经验

Evaluation of intraoperative MRI-assisted stereotactic brain tissue biopsy: a single-center experience in China.

作者信息

Lu Chang-Yu, Xu Zong-Sheng, Ye Xun

机构信息

Department of Neurosurgery, Peking University International Hospital, Beijing, China.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

Chin Neurosurg J. 2019 Feb 15;5:4. doi: 10.1186/s41016-019-0152-0. eCollection 2019.

DOI:10.1186/s41016-019-0152-0
PMID:32922904
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7398305/
Abstract

BACKGROUND

This study aimed to investigate the value of high field-strength intraoperative magnetic resonance imaging (iMRI)-guided stereotactic biopsy in the surgery of intracranial space-occupying lesions.

METHODS

A total of 87 patients who underwent stereotactic biopsy of intracranial lesions in the Peking University International Hospital from March 2016 to August 2018 were retrospectively surveyed; among these, 50 patients underwent MRI-guided stereotactic biopsy using the Leksell frame (iMRI group) and 37 cases received traditional stereotactic biopsy using the Leksell frame (control group). The accuracy rates and complications of the two groups were compared.

RESULTS

A 100% positive diagnosis was observed in all cases ( = 50) in the iMRI group. In 4 cases, the biopsy site was clearly found to have deviated from the target point, and the biopsy was performed again. The control group had 33 cases (86.5%) with positive diagnosis. No severe complications like neural functional deficit were observed in the iMRI group, while two patients developed bleeding at the puncture site (1 case receiving surgery to remove the hematoma) in the control group. There were no deaths in either group.

CONCLUSION

iMRI-assisted stereotactic biopsy can confirm the target position and adjust the puncture path in real time. Compared to the traditional stereotactic biopsy technique, the iMRI method has a higher positive diagnostic rate, though surgical trauma and complications have no significant difference.

摘要

背景

本研究旨在探讨高场强术中磁共振成像（iMRI）引导下立体定向活检在颅内占位性病变手术中的价值。

方法

回顾性调查2016年3月至2018年8月在北京大学国际医院接受颅内病变立体定向活检的87例患者；其中，50例患者使用Leksell框架进行MRI引导下立体定向活检（iMRI组），37例接受传统Leksell框架立体定向活检（对照组）。比较两组的准确率和并发症。

结果

iMRI组所有病例（n = 50）诊断均为阳性。4例患者活检部位明显偏离靶点，再次进行活检。对照组33例（86.5%）诊断为阳性。iMRI组未观察到神经功能缺损等严重并发症，而对照组有2例患者穿刺部位出血（1例接受手术清除血肿）。两组均无死亡病例。

结论

iMRI辅助立体定向活检可实时确认靶点位置并调整穿刺路径。与传统立体定向活检技术相比，iMRI方法阳性诊断率更高，虽然手术创伤和并发症无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/b0c839ae7bff/41016_2019_152_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/e3206af992da/41016_2019_152_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/0a55edeced9c/41016_2019_152_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/677761323ef0/41016_2019_152_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/1b93f0e1ecab/41016_2019_152_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/535dd6fc11d0/41016_2019_152_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/f25eedf3f7cc/41016_2019_152_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/29d664bd0c50/41016_2019_152_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/145e89eea85c/41016_2019_152_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/6ee0109f2fd0/41016_2019_152_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/b0c839ae7bff/41016_2019_152_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/e3206af992da/41016_2019_152_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/0a55edeced9c/41016_2019_152_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/677761323ef0/41016_2019_152_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/1b93f0e1ecab/41016_2019_152_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/535dd6fc11d0/41016_2019_152_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/f25eedf3f7cc/41016_2019_152_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/29d664bd0c50/41016_2019_152_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/145e89eea85c/41016_2019_152_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/6ee0109f2fd0/41016_2019_152_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c7c/7398305/b0c839ae7bff/41016_2019_152_Fig10_HTML.jpg

相似文献

1
Evaluation of intraoperative MRI-assisted stereotactic brain tissue biopsy: a single-center experience in China.术中磁共振成像辅助立体定向脑组织活检的评估：中国单中心经验
Chin Neurosurg J. 2019 Feb 15;5:4. doi: 10.1186/s41016-019-0152-0. eCollection 2019.
2
Intraoperative visualisation of functional structures facilitates safe frameless stereotactic biopsy in the motor eloquent regions of the brain.术中对功能结构的可视化有助于在大脑运动功能区进行安全的无框架立体定向活检。
Br J Neurosurg. 2018 Aug;32(4):372-380. doi: 10.1080/02688697.2017.1416059. Epub 2017 Dec 20.
3
Role of high-field intraoperative magnetic resonance imaging on a multi-image fusion-guided stereotactic biopsy of the basal ganglia: A case report.高场强术中磁共振成像在基底节区多图像融合引导立体定向活检中的作用：一例报告
Oncol Lett. 2015 Jan;9(1):223-226. doi: 10.3892/ol.2014.2680. Epub 2014 Nov 7.
4
[Values of stereotactic guidance of intraoperative high-field magnetic resonance imaging for multiple intracranial lesions].术中高场磁共振成像立体定向引导对颅内多发病变的价值
Zhonghua Yi Xue Za Zhi. 2014 Nov 25;94(43):3421-4.
5
[Stereotactic brain biopsy guided by iMRI co-registration combined with PET/CT].磁共振成像引导下立体定向脑活检联合正电子发射断层显像/计算机断层扫描
Zhonghua Yi Xue Za Zhi. 2016 Mar 8;96(9):685-8. doi: 10.3760/cma.j.issn.0376-2491.2016.09.004.
6
[Automated proton magnetic resonance spectroscopy imaging guided frameless stereotactic biopsy of intracranial lesions].[自动质子磁共振波谱成像引导下颅内病变的无框架立体定向活检]
Zhonghua Wai Ke Za Zhi. 2014 Apr;52(4):280-4.
7
[Implementation of multimodal navigation combined with intraoperative magnetic resonance imaging in the frameless stereotactic biopsy of intracranial lesions].[多模态导航联合术中磁共振成像在颅内病变无框架立体定向活检中的应用]
Zhonghua Yi Xue Za Zhi. 2017 Aug 1;97(29):2288-2292. doi: 10.3760/cma.j.issn.0376-2491.2017.29.012.
8
Intraoperative magnetic resonance-guided frameless stereotactic biopsies - initial clinical experience.术中磁共振引导无框架立体定向活检 - 初步临床经验。
Neurol Neurochir Pol. 2012 Mar-Apr;46(2):157-60. doi: 10.5114/ninp.2012.28258.
9
Frame-based stereotactic biopsies using an intraoperative MR-scanner are as safe and effective as conventional stereotactic procedures.基于框架的立体定向活检使用术中磁共振扫描仪与传统的立体定向手术一样安全有效。
PLoS One. 2018 Oct 23;13(10):e0205772. doi: 10.1371/journal.pone.0205772. eCollection 2018.
10
Intraoperative MRI for optimizing electrode placement for deep brain stimulation of the subthalamic nucleus in Parkinson disease.术中磁共振成像用于优化帕金森病丘脑底核深部脑刺激电极置入
J Neurosurg. 2016 Jan;124(1):62-9. doi: 10.3171/2015.1.JNS141534. Epub 2015 Aug 14.

引用本文的文献

1
Surgical results in patients with CNS lymphoma. Comparison of predictive value of intraoperative MRI and intraoperative histological examination for diagnostic biopsy yield.中枢神经系统淋巴瘤患者的手术结果。术中磁共振成像与术中组织学检查对诊断性活检取材的预测价值比较。
Brain Spine. 2024 Oct 18;4:103926. doi: 10.1016/j.bas.2024.103926. eCollection 2024.
2
Comparison meta-analysis of intraoperative MRI-guided needle biopsy versus conventional stereotactic needle biopsies.术中磁共振成像引导下针吸活检与传统立体定向针吸活检的比较荟萃分析
Neurooncol Adv. 2023 Oct 10;6(1):vdad129. doi: 10.1093/noajnl/vdad129. eCollection 2024 Jan-Dec.
3

本文引用的文献

1
Complications Following Stereotactic Needle Biopsy of Intracranial Tumors.颅内肿瘤立体定向穿刺活检后的并发症
World Neurosurg. 2015 Oct;84(4):1084-9. doi: 10.1016/j.wneu.2015.05.025. Epub 2015 May 22.
2
Intraindividual comparison of histopathological diagnosis obtained by stereotactic serial biopsy to open surgical resection specimen in patients with intracranial tumours.颅内肿瘤患者立体定向系列活检与开放性手术切除标本的组织病理学诊断的个体内比较。
Clin Neurol Neurosurg. 2013 Oct;115(10):1955-60. doi: 10.1016/j.clineuro.2013.05.019. Epub 2013 Jun 14.
3
Stereotactic brain biopsy with a low-field intraoperative magnetic resonance imager.
Indicators of correct targeting in stereotactic biopsy of intracranial lesions.
颅内病变立体定向活检中正确靶向的指标。
Surg Neurol Int. 2022 Jun 17;13:251. doi: 10.25259/SNI_246_2022. eCollection 2022.
立体定向脑活检术与低场术中磁共振成像。
Neurosurgery. 2011 Mar;68(1 Suppl Operative):217-24; discussion 224. doi: 10.1227/NEU.0b013e31820826c2.
4
Towards improving the safety and diagnostic yield of stereotactic biopsy in a single centre.提高单中心立体定向活检安全性和诊断产量的方法。
Acta Neurochir (Wien). 2010 Nov;152(11):1915-21. doi: 10.1007/s00701-010-0752-0. Epub 2010 Aug 1.
5
Frame-based stereotaxy in a frameless era: current capabilities, relative role, and the positive- and negative predictive values of blood through the needle.在无框架时代的基于框架的立体定向技术：当前能力、相对作用以及针吸血液的阳性和阴性预测值。
J Neurooncol. 2009 May;93(1):139-49. doi: 10.1007/s11060-009-9871-y. Epub 2009 May 9.
6
Comparative analysis of diagnostic accuracy of different brain biopsy procedures.不同脑活检程序诊断准确性的比较分析
Neurol India. 2006 Dec;54(4):394-8. doi: 10.4103/0028-3886.28113.
7
Frameless stereotactic surgery using intraoperative high-field magnetic resonance imaging.使用术中高场磁共振成像的无框架立体定向手术
Neurol Med Chir (Tokyo). 2004 Oct;44(10):522-33; discussion 534. doi: 10.2176/nmc.44.522.
8
Histological yield, complications, and technological considerations in 114 consecutive frameless stereotactic biopsy procedures aided by open intraoperative magnetic resonance imaging.114例连续的术中开放式磁共振成像辅助无框架立体定向活检手术的组织学取材量、并发症及技术要点
J Neurosurg. 2002 Aug;97(2):354-62. doi: 10.3171/jns.2002.97.2.0354.
9
A four-year experience with a stereotactic computer in a small neurosurgical department.一个小型神经外科科室使用立体定向计算机的四年经验。
Surg Neurol. 2002 Mar;57(3):190-4. doi: 10.1016/s0090-3019(01)00700-5.
10
An integrated visualization system for surgical planning and guidance using image fusion and an open MR.一种使用图像融合和开放式磁共振成像进行手术规划与引导的集成可视化系统。
J Magn Reson Imaging. 2001 Jun;13(6):967-75. doi: 10.1002/jmri.1139.