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舒尼替尼：转移性嫌色细胞肾细胞癌患者气胸的罕见病因。

Sunitinib: An Unusual Cause of Pneumothorax in a Patient With Metastatic Chromophobe Renal Cell Carcinoma.

作者信息

Bukhari Nedal, Al-Badr Suha, AlNaimi Manal, Azam Faisal

机构信息

Medical Oncology, King Fahad Specialist Hopsital, Dammam, SAU.

Internal Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

出版信息

Cureus. 2020 Aug 6;12(8):e9586. doi: 10.7759/cureus.9586.

DOI:10.7759/cureus.9586
PMID:32923192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7478553/
Abstract

Spontaneous pneumothorax secondary to sunitinib, a vascular endothelial growth factor receptor (VEGFR) inhibitor, is an extremely rare side effect of this class of medications. In this report, we present the case of a patient with metastatic renal cell carcinoma (RCC) who developed bilateral pneumothoraces after starting on sunitinib. This case report recognizes pneumothorax as a life-threatening side effect of sunitinib.

摘要

舒尼替尼是一种血管内皮生长因子受体（VEGFR）抑制剂，继发于舒尼替尼的自发性气胸是这类药物极为罕见的副作用。在本报告中，我们介绍了一例转移性肾细胞癌（RCC）患者，该患者在开始使用舒尼替尼后出现双侧气胸。本病例报告确认气胸是舒尼替尼的一种危及生命的副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/f5a38bb81e79/cureus-0012-00000009586-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/f1e845a3e8ff/cureus-0012-00000009586-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/6cb6803cbb57/cureus-0012-00000009586-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/f5a38bb81e79/cureus-0012-00000009586-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/f1e845a3e8ff/cureus-0012-00000009586-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/6cb6803cbb57/cureus-0012-00000009586-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11be/7478553/f5a38bb81e79/cureus-0012-00000009586-i03.jpg

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Case: Secondary polycythemia due to pazopanib in patients with metastatic renal cell carcinoma.病例：转移性肾细胞癌患者因帕唑帕尼导致的继发性红细胞增多症。
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依维莫司对比舒尼替尼治疗转移性非透明细胞肾细胞癌患者（ASPEN）：一项多中心、开放标签、随机2期试验
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