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人工耳蜗感染及结果:单一大中心经验

Cochlear Implant Infections and Outcomes: Experience From a Single Large Center.

机构信息

Department of ENT, Addenbrookes' Hospital, Cambridge University Hospital Trust, Cambridge, UK.

出版信息

Otol Neurotol. 2020 Oct;41(9):e1105-e1110. doi: 10.1097/MAO.0000000000002772.

DOI:10.1097/MAO.0000000000002772
PMID:32925845
Abstract

OBJECTIVE

To review our experience with cochlear implant infections over the past 5 years, the management strategy and to identify predictive factors that led to explantation.

STUDY DESIGN

Retrospective record-base case series of cochlear implant infections.

SETTING

Tertiary otology and implant center.

PATIENTS

All patients who had cochlear implantation over a period of 5 years.

INTERVENTION(S): None.

MAIN OUTCOME MEASURE(S): To identify risk factors, rates and outcomes of cochlear implant infections, and to formulate strategies to develop clearer management protocols to prevent cochlear implant explantation.

RESULTS

Of 704 implanted patients, 22 suffered a postoperative soft tissue infection (3%). Fifty-nine percent of these infected patients resulted in explantation, giving an explantation rate of 1.8% over the whole study population. One hundred percent of the infected implants identified as having either Staph. Aureus or Pseudomonas spp. as the single causative organism resulted in explantation.

CONCLUSIONS

There is a high rate of explantation when infection is detected. Currently there is no clear consensus on medical management, such as choice of antibiotics or length of antibiotic course. A registry of cochlear implants would facilitate standard reporting methods for severity and type of infection, to be able to pool data across centers and form a more robust management protocol for cochlear implant infections.

摘要

目的

回顾过去 5 年来我们在人工耳蜗感染方面的经验、管理策略以及确定导致取出的预测因素。

研究设计

回顾性记录基础病例系列的人工耳蜗感染。

设置

三级耳科学和植入中心。

患者

在 5 年内接受人工耳蜗植入的所有患者。

干预措施

无。

主要观察指标

确定人工耳蜗感染的风险因素、发生率和结果,并制定策略以制定更明确的管理方案,以防止人工耳蜗取出。

结果

在 704 名植入患者中,有 22 名患者出现术后软组织感染(3%)。这些感染患者中有 59%导致取出,在整个研究人群中,取出率为 1.8%。100%的感染植入物确定为金黄色葡萄球菌或铜绿假单胞菌单一病原体,导致取出。

结论

当检测到感染时,取出的概率很高。目前,对于抗生素的选择或抗生素疗程的长短等医疗管理,还没有明确的共识。人工耳蜗植入物登记处将促进严重程度和感染类型的标准报告方法,以便能够在中心之间汇总数据,并为人工耳蜗感染制定更稳健的管理方案。

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