Ogbu Ikechukwu Martin, Lusseau Jonathan, Kurtay Gülbin, Robert Frédéric, Landais Yannick
University of Bordeaux, Institute of Molecular Sciences (ISM), UMR-CNRS 5255, 351, Cours de la Libération, 33405 Talence Cedex, France.
Chem Commun (Camb). 2020 Oct 13;56(81):12226-12229. doi: 10.1039/d0cc05069e.
Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.
报道了在温和的电化学条件下通过草氨酸的氧化脱羧合成聚氨酯。这种简单的无光气合成聚氨酯的方法涉及在醇介质中通过草氨酸的阳极氧化原位生成异氰酸酯。该反应适用于多种草氨酸，包括手性草氨酸，并且在不使用化学氧化剂的情况下，通过一锅法由醇类生成所需的聚氨酯。
