Hess C F, Griebel J, Schmiedl U, Kurtz B, Koelbel G, Jaehde E
Radiologische Klinik, Universitaet, Tuebingen, F.R.G.
J Comput Assist Tomogr. 1988 Jul-Aug;12(4):569-74. doi: 10.1097/00004728-198807000-00005.
Sixteen patients with splenic lymphoma and six with nonlymphomatous splenic lesions underwent magnetic resonance (MR) imaging, ultrasound (US), and dynamic CT. All patients were studied at 1.5 T with gradient echo sequences using a repetition time of 80 ms, echo time of 16 ms, and two pulse angles of 30 and 60 degrees. In 14 patients with lymphomatous lesions fast MR showed circumscribed areas of low signal intensity at both pulse angles. The lesion-to-spleen contrast was better on images acquired with a pulse angle of 30 degrees. For fast MR with pulse angles of 30 degrees, the mean lesion-to-spleen contrast was similar to US and contrast-enhanced CT. However, with fast MR the contrast showed a lower variability and was considerably better than with unenhanced CT. In one patient fast MR showed splenic involvement that was missed on both CT and US. The signal characteristics of lymphomatous, leukemic, and sarcoid involvement and of healed infarcts were similar and indistinguishable on fast MR images. Recent splenic infarctions (three cases) were, however, distinctly different, characterized by regions of high signal intensity at both pulse angles. The results of this preliminary study suggest that fast MR imaging is a promising diagnostic tool for the assessment of splenic disorders.
16例脾淋巴瘤患者和6例非淋巴瘤性脾病变患者接受了磁共振（MR）成像、超声（US）和动态CT检查。所有患者均在1.5T磁场下，使用梯度回波序列进行研究，重复时间为80ms，回波时间为16ms，两个脉冲角度分别为30度和60度。在14例淋巴瘤性病变患者中，快速MR在两个脉冲角度下均显示出边界清晰的低信号强度区域。在脉冲角度为30度采集的图像上，病变与脾脏的对比度更好。对于脉冲角度为30度的快速MR，病变与脾脏的平均对比度与US和增强CT相似。然而，快速MR的对比度变异性较低，且明显优于未增强CT。在1例患者中，快速MR显示出CT和US均未发现的脾脏受累情况。淋巴瘤、白血病和结节病累及以及愈合梗死在快速MR图像上的信号特征相似且难以区分。然而，近期脾梗死（3例）表现明显不同，在两个脉冲角度下均表现为高信号强度区域。这项初步研究结果表明，快速MR成像对于评估脾脏疾病是一种有前景的诊断工具。
