Collaborative Data Services Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
Methods Mol Biol. 2021;2194:35-44. doi: 10.1007/978-1-0716-0849-4_3.
Translational studies for therapeutic development require cohort identification to identify appropriate biological materials from patients that can be utilized to test a specific hypothesis. Robust health information systems exist, but there are numerous challenges in accessing the information to select appropriate biological specimens needed for translational experiments. This chapter on methods describes the current standard process for cohort identification utilized by the Cutaneous Oncology Program and the Collaborative Data Services Core (CDSC) at Moffitt Cancer Center. The methods include utilization of graphical user interfaces coupled with database querying. As such, this chapter outlines the regulatory and procedural processes needed to utilize a health information management system to filter patients for cohort identification.
治疗开发的转化研究需要队列识别，以从患者中识别出可用于测试特定假设的合适生物材料。现有的健康信息系统是健全的，但在获取信息以选择转化实验所需的合适生物标本方面存在诸多挑战。本章介绍了方法，描述了莫菲特癌症中心皮肤肿瘤计划和协作数据服务核心（CDSC）目前使用的队列识别标准流程。该方法包括使用图形用户界面与数据库查询相结合。因此，本章概述了利用健康信息管理系统筛选患者进行队列识别所需的监管和程序流程。
