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132 例医护人员 COVID-19 病例的临床特征:来自中国武汉单中心的回顾性研究。

Clinical characteristics of 132 healthcare worker cases with COVID-19: A retrospective study from a single center in Wuhan, China.

机构信息

Renmin Hospital of Wuhan University, Ophthalmology, Wuhan, Hubei, China.

Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong, China.

出版信息

J Med Virol. 2021 Mar;93(3):1631-1638. doi: 10.1002/jmv.26511. Epub 2020 Sep 28.

Abstract

Many healthcare workers (HCWs) have been confirmed to be infected with SARS-CoV-2 in China. A retrospective, single-center study was conducted. The median age of the 132 HCWs with COVID-19 was 32 years, with 92 (69.7%) being females. There were 47 (35.6%) doctors, 72 (54.6%) nurses, and 13 (9.9%) other HCWs. Ten of the 132 patients (7.6%) had underlying diseases. The most common symptoms of illness onset were fever (70, 53.0%), cough (66, 50.0%), and fatigue (58, 43.9%). All patients were categorized into mild or moderate COVID-19 type on admission to hospital, and five (3.8%) progressed to the severe COVID-19 type. Sixty-six HCWs patients were included in both the early and later discharged group. In the logistic analysis, the later discharged patients had a longer time for illness onset to hospital admission (per 1 day; OR, 1.10; 95% CI, 1.03-1.18; p = .006), a higher proportion of >3 onset symptoms clustering (OR, 3.11; 95% CI, 1.27-7.62; p = .01), and a higher percentage of other HCWs (OR, 6.20; 95% CI, 1.49-25.80; p = .01). HCW patients were young female nurses with fewer comorbidities, and most were mild or moderate COVID-19 type. The later discharged patients exhibited characteristics of longer time for illness onset to hospitalization and clustering of onset symptoms.

摘要

许多医护人员(HCWs)已被证实在中国感染了 SARS-CoV-2。一项回顾性、单中心研究进行了。132 名 COVID-19 感染 HCWs 的中位年龄为 32 岁,92 名(69.7%)为女性。其中 47 名(35.6%)为医生,72 名(54.6%)为护士,13 名(9.9%)为其他 HCWs。132 名患者中有 10 名(7.6%)有基础疾病。发病最常见的症状是发热(70 例,53.0%)、咳嗽(66 例,50.0%)和疲劳(58 例,43.9%)。所有患者入院时均被归类为轻度或中度 COVID-19 型,5 例(3.8%)进展为重度 COVID-19 型。66 名 HCWs 患者同时被纳入早期和晚期出院组。在逻辑分析中,晚期出院的患者从发病到住院的时间更长(每 1 天;OR,1.10;95%CI,1.03-1.18;p=0.006),发病症状聚类的比例更高(OR,3.11;95%CI,1.27-7.62;p=0.01),其他 HCWs 的比例更高(OR,6.20;95%CI,1.49-25.80;p=0.01)。HCW 患者是年轻的女性护士,合并症较少,大多数为轻度或中度 COVID-19 型。晚期出院的患者表现出发病至住院时间较长和发病症状聚类的特征。

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