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用于评估和治疗肺栓塞的替代诊断策略:病例系列

Alternative Diagnostic Strategy for the Assessment and Treatment of Pulmonary Embolus: A Case Series.

作者信息

Aghayev Ayaz, Memon Aliza A, Greenough Paul Gregg, Nayak Lakshmi, Zheng Sijie, Siedlecki Andrew M

机构信息

Brigham and Women's Hospital, Department of Radiology, Boston, Massachusetts.

Brigham and Women's Hospital, Department of Internal Medicine, Boston, Massachusetts.

出版信息

Clin Pract Cases Emerg Med. 2020 Aug;4(3):308-311. doi: 10.5811/cpcem.2020.5.46517.

DOI:10.5811/cpcem.2020.5.46517
PMID:32926673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7434252/
Abstract

INTRODUCTION

Ferumoxytol-enhanced magnetic resonance angiography (FeMRA) can be used as an alternate and safe method to diagnose patients with compromised renal function who present with acute pulmonary embolus in the emergency department (ED) setting.

CASE REPORT

A 62-year old man with a history of renal transplant and lymphoproliferative disease described new onset of breathlessness. His clinical symptoms were suggestive of pulmonary embolus. He underwent FeMRA in the ED to avoid exposure to intravenous iodinated contrast. FeMRA demonstrated a left main pulmonary artery embolus, which extended to the left interlobar pulmonary artery. Afterward, the patient initiated anticoagulation therapy. With preserved renal function he was able to continue his outpatient chemotherapy regimen.

CONCLUSION

This case highlights a safe imaging technique for emergency physicians to diagnose pulmonary embolus and subsequently guide anticoagulation therapy for patients in whom use of conventional contrast is contraindicated.

摘要

引言

铁羧麦芽糖增强磁共振血管造影(FeMRA)可作为一种替代且安全的方法,用于诊断在急诊科(ED)出现急性肺栓塞且肾功能受损的患者。

病例报告

一名62岁男性,有肾移植和淋巴增殖性疾病史,自述新发呼吸困难。其临床症状提示肺栓塞。他在急诊科接受了FeMRA检查,以避免接触静脉注射碘造影剂。FeMRA显示左主肺动脉栓塞,延伸至左叶间肺动脉。之后,患者开始抗凝治疗。由于肾功能保留,他能够继续其门诊化疗方案。

结论

本病例突出了一种安全的成像技术,可供急诊医生用于诊断肺栓塞,并随后指导对禁忌使用传统造影剂的患者进行抗凝治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/5d8ae35e9b33/cpcem-04-308-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/33c724b567a2/cpcem-04-308-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/2937bf090017/cpcem-04-308-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/5d8ae35e9b33/cpcem-04-308-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/33c724b567a2/cpcem-04-308-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/2937bf090017/cpcem-04-308-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab4/7434252/5d8ae35e9b33/cpcem-04-308-g003.jpg

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本文引用的文献

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Radiology. 2019 Dec;293(3):554-564. doi: 10.1148/radiol.2019190477. Epub 2019 Oct 22.
2
Cancer in kidney transplant recipients.肾移植受者中的癌症。
Nat Rev Nephrol. 2018 Aug;14(8):508-520. doi: 10.1038/s41581-018-0022-6.
3
Estimated glomerular filtration rate in stable older kidney transplant recipients-are present algorithms valid? A national cross-sectional cohort study.稳定期老年肾移植受者的估计肾小球滤过率:现有算法是否有效?一项全国性的横断面队列研究。
Transpl Int. 2018 Jun;31(6):629-638. doi: 10.1111/tri.13137. Epub 2018 Mar 14.
4
Ferumoxytol-enhanced magnetic resonance angiography for the assessment of potential kidney transplant recipients.铁氧体增强磁共振血管造影用于评估潜在的肾移植受者。
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Current and potential imaging applications of ferumoxytol for magnetic resonance imaging.菲洛米莫用于磁共振成像的当前及潜在成像应用
Kidney Int. 2017 Jul;92(1):47-66. doi: 10.1016/j.kint.2016.12.037. Epub 2017 Apr 20.
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Risk of Acute Kidney Injury After Intravenous Contrast Media Administration.静脉注射造影剂后急性肾损伤的风险
Ann Emerg Med. 2017 May;69(5):577-586.e4. doi: 10.1016/j.annemergmed.2016.11.021. Epub 2017 Jan 25.
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Incidences of acute kidney injury, dialysis, and graft loss following intravenous administration of low-osmolality iodinated contrast in patients with kidney transplants.肾移植患者静脉注射低渗碘造影剂后急性肾损伤、透析和移植物丢失的发生率。
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