Takahashi K, Yoshino K, Shirai T, Nishigaki A, Araki Y, Kitao M
Department of Obstetrics and Gynecology, Shimane Medical University.
Nihon Sanka Fujinka Gakkai Zasshi. 1988 Jun;40(6):789-92.
In 20 infertile Japanese with polycystic ovary syndrome Shakuyaku-Kanzo-To was used to lower plasma testosterone levels and hence to induce pregnancy. The polycystic ovary was classified into two types; general cystic and peripheral cystic patterns. Plasma testosterone was decreased in 18/20 (90%) and 5/20 (25%) became pregnant. The plasma testosterone concentration in the case of the general cystic pattern was significantly higher than that of peripheral cystic pattern, and the pregnancy rate in those with the general cystic pattern was lower. The efficacy of Shakuyaku-Kanzo-To therefore seems to vary according to the type of polycystic ovary syndrome treated.
在20名患有多囊卵巢综合征的日本不育患者中,使用芍药甘草汤来降低血浆睾酮水平,从而诱导怀孕。多囊卵巢被分为两种类型:一般囊肿型和周边囊肿型。18/20(90%)的患者血浆睾酮水平下降,5/20(25%)的患者怀孕。一般囊肿型患者的血浆睾酮浓度显著高于周边囊肿型患者,且一般囊肿型患者的怀孕率较低。因此,芍药甘草汤的疗效似乎因所治疗的多囊卵巢综合征类型而异。