Stuhrmann H B, Koch M H, Parfait R, Haas J, Ibel K, Crichton R R
Proc Natl Acad Sci U S A. 1977 Jun;74(6):2316-20. doi: 10.1073/pnas.74.6.2316.
Extrapolation of a series of low-angle neutron scattering curves to infinitely high contrast gives a scattering function IC(kappa) which is dependent on the shape of the solute molecule. For the 50S subunit of E. coli ribosomes, the first part of the structure determination by neutron scattering, namely the determination of the molecular shape from IC(kappa), is reported. The result is in good agreement with models of the 50S subunit determined by electron microscopy.
将一系列低角度中子散射曲线外推至无限高的对比度,可得到一个依赖于溶质分子形状的散射函数IC(κ)。本文报道了通过中子散射确定大肠杆菌核糖体50S亚基结构的第一部分,即从IC(κ)确定分子形状。结果与通过电子显微镜确定的50S亚基模型高度吻合。