大肠杆菌核糖体50S亚基的新型低分辨率模型。
New low resolution model for 50S subunit of Escherichia coli ribosomes.
作者信息
Stuhrmann H B, Haas J, Ibel K, Wolf B, Koch M H, Parfait R, Crichton R R
出版信息
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2379-83. doi: 10.1073/pnas.73.7.2379.
Abstract
Neutron low angle scattering studies of the 50S subunit of E. coli ribosomes with the contrast variation method reveals large fluctuations in the scattering density. A region of relatively low scattering density, rich in proteins, surrounds an RNA-rich core of higher scattering density. The centers of mass of the RNA and protein parts of the 50S subunit are separated by a distance (20 A) that is considerably smaller than that reported in previous studies.
摘要
利用对比变化法对大肠杆菌核糖体50S亚基进行的中子低角度散射研究揭示了散射密度的大幅波动。一个散射密度相对较低、富含蛋白质的区域围绕着一个散射密度较高、富含RNA的核心。50S亚基的RNA和蛋白质部分的质心相距一段距离（20埃），该距离比之前研究报道的要小得多。
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