基于无标记量子点对铜离子和银离子的区分。

Discrimination of copper and silver ions based on the label-free quantum dots.

机构信息

Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China.

Chongqing Key Laboratory of Biomedical Analysis (Southwest University), Chongqing Science & Technology Commission, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.

出版信息

Talanta. 2020 Dec 1;220:121430. doi: 10.1016/j.talanta.2020.121430. Epub 2020 Jul 22.

DOI:10.1016/j.talanta.2020.121430

PMID:32928435

Abstract

A simple and fast method for copper ions (Cu) and silver ions (Ag) detection was established with cadmium telluride quantum dots (CdTe QDs) as fluorescent probes. In the presence of Cu or Ag, the fluorescence intensity of TGA-CdTe QD can be significantly quenched, which fitted a linear relationship between the fluorescence quenching degree (F-F)/F and the concentration of metal ions. In this work, the lowest detected concentration for Cu and Ag was 35.0 nM and 25.3 nM, respectively. In addition, the differentiation of Cu and Ag at different concentrations was realized with the principal component analysis (PCA). Furthermore, Cu was successfully detected in body fluids. This method provides a good potential for copper ions and silver ions detection with simplicity, rapidity, and excellent selectivity.

摘要

一种简单快速的铜离子(Cu)和银离子(Ag)检测方法，以碲化镉量子点(CdTe QDs)为荧光探针。在存在 Cu 或 Ag 的情况下，TGA-CdTe QD 的荧光强度可以被显著猝灭，荧光猝灭程度(F-F)/F 与金属离子浓度之间呈线性关系。在这项工作中，Cu 和 Ag 的最低检测浓度分别为 35.0 nM 和 25.3 nM。此外，通过主成分分析(PCA)实现了不同浓度下 Cu 和 Ag 的区分。此外，还成功地在体液中检测到了 Cu。该方法具有简单、快速和优异选择性的特点，为铜离子和银离子的检测提供了良好的应用前景。