Department of Rehabilitation Medicine, The Chinese PLA General Hospital, Beijing, China.
Department of Rehabilitation Medicine, The Chinese PLA General Hospital, Beijing, China.
J Manipulative Physiol Ther. 2020 Jun;43(5):506-514. doi: 10.1016/j.jmpt.2019.05.008. Epub 2020 Sep 12.
This study aimed to investigate the effect of dry needling (DN) with 44°C heating on the pressure pain threshold (PPT) of rats with chronic myofascial pain syndrome (MPS) by regulating the transient receptor potential V1 channel.
A total of 80 rats were divided into 5 groups: A, B, C, D, and E (16 in each group). The rats in Group A recovered naturally, while those in other groups received the DN treatment. The needles were heated to 40°C for the rats in Groups B and E and 44°C for the rats in Groups C and D. In addition, both Groups D and E received local capsaicin injection. PPTs of the gastrocnemius muscle and tolerance time of the plantar hot plate were measured before modeling, 1 day before the intervention, 24 hours after the intervention, and 7 days after the intervention.
PPTs of the gastrocnemius muscle for rats with MPS increased 7 days after DN and heating to 40°C. For the rats receiving DN at 44°C heating, PPTs increased 24 hours and 7 days after the intervention. Further, 44°C heating and capsaicin injection improved PPT. DN and 40°C heating followed by capsaicin injection improved PPT.
DN and 44°C heating had therapeutic effects on rats with MPS at 24 hours and at 7 days after the intervention. DN and 40°C heating had therapeutic effects 7 days after the intervention. DN and 44°C heating might exert therapeutic effects by regulating the transient receptor potential V1 channel.
本研究旨在通过调节瞬时受体电位 V1 通道，探讨 44°C 加热干针（DN）对慢性肌筋膜疼痛综合征（MPS）大鼠的压力疼痛阈值（PPT）的影响。
将 80 只大鼠分为 5 组：A、B、C、D 和 E（每组 16 只）。A 组大鼠自然恢复，其他组大鼠接受 DN 治疗。B 组和 E 组大鼠的针加热至 40°C，C 组和 D 组大鼠的针加热至 44°C。此外，D 组和 E 组大鼠均接受局部辣椒素注射。在建模前、干预前 1 天、干预后 24 小时和干预后 7 天测量大鼠腓肠肌 PPT 和足底热板耐受时间。
DN 和 40°C 加热后，MPS 大鼠腓肠肌 PPT 在 7 天增加。44°C 加热和 DN 治疗后，大鼠 PPT 在 24 小时和 7 天增加。此外，44°C 加热和辣椒素注射可提高 PPT。DN 和 40°C 加热后注射辣椒素可提高 PPT。
DN 和 44°C 加热在干预后 24 小时和 7 天对 MPS 大鼠有治疗作用。DN 和 40°C 加热在干预后 7 天有治疗作用。DN 和 44°C 加热可能通过调节瞬时受体电位 V1 通道发挥治疗作用。
