Department of Surgical, Oncological and Oral Sciences, Policlinico P. Giaccone, University of Palermo, Via Liborio Giuffré 5, 90127, Palermo, Italy.
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Policlinico P. Giaccone, University of Palermo, 90127, Palermo, Italy.
Hernia. 2021 Aug;25(4):999-1004. doi: 10.1007/s10029-020-02302-7. Epub 2020 Sep 14.
Hernias severely impact patient quality of life (QoL), and 80% of patients require a surgical operation. Moreover, hernias are responsible for respiratory function alterations. This study aims to investigate the postoperative alterations in respiratory function after open ventral hernia repair in patients with incisional hernia.
Patients operated on at the Policlinico "Paolo Giaccone" at Palermo University Hospital between January 2015 and December 2016 were identified in a prospective database. Fifty-one patients were enrolled in the study. The respiratory outcome measures used were forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FEV1/FVC ratio, peak expiratory flow (PEF) and PEF percentage (%PEF). The timepoints at which the parameters listed were assessed were t, 1 week before the surgical operation; t, 12 months later; and t, 3 years later.
The difference between mean preoperative and postoperative PEF was significant [t 4.32 (4.03-7.92), t 6.7 (4.27-8.24) with p = 0.012 and t 6.5 (4.25-8.21) with p = 0.026]. The %PEF increased from 75% preoperatively to 87% at t (p = 0.009) and to 85% at t (p = 0.03). No differences were found in the comparison of pre- and postoperative FVC, FEV1 or FEV1/FVC ratio.
The improvement in respiratory measures suggests the importance of abdominal wall restoration to recover functional activity of respiratory function.
疝严重影响患者的生活质量（QoL），80%的患者需要手术。此外，疝会导致呼吸功能改变。本研究旨在探讨切开疝修补术后开放腹疝患者呼吸功能的术后变化。
在 2015 年 1 月至 2016 年 12 月期间，在巴勒莫大学医院的 Policlinico“Paolo Giaccone”对接受手术的患者进行前瞻性数据库识别。共有 51 名患者纳入研究。使用的呼吸结局测量指标包括用力肺活量（FVC）、1 秒用力呼气量（FEV1）、FEV1/FVC 比值、呼气峰流速（PEF）和 PEF 百分比（%PEF）。评估参数的时间点为 t，手术前 1 周；t，术后 12 个月；和 t，术后 3 年。
平均术前和术后 PEF 的差异具有统计学意义[t 4.32（4.03-7.92），t 6.7（4.27-8.24）p=0.012 和 t 6.5（4.25-8.21）p=0.026]。%PEF 从术前的 75%增加到 t 时的 87%（p=0.009）和 t 时的 85%（p=0.03）。FVC、FEV1 或 FEV1/FVC 比值的术前与术后比较无差异。
呼吸测量指标的改善表明腹壁重建对恢复呼吸功能的功能性活动的重要性。
