Liang Yong-Xin, Yang Ming, He Bo-Wen, Zhao Yu-Long
Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Faculty of Chemistry, Northeast Normal University, Changchun 130024, China.
Org Lett. 2020 Oct 2;22(19):7640-7644. doi: 10.1021/acs.orglett.0c02835. Epub 2020 Sep 15.
A silver-catalyzed cascade cyclization reaction of isocyanides with sulfoxonium ylides has been developed for the first time. This reaction provides a new and efficient method for the construction of highly functionalized 3-aminofurans and 4-aminoquinolines from readily available starting materials in a single step.
首次开发了一种银催化的异腈与亚砜叶立德的串联环化反应。该反应提供了一种新的有效方法，可从容易获得的起始原料一步构建高度官能化的3-氨基呋喃和4-氨基喹啉。
