Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.
Liaoning Provincial Center for Disease Control and Prevention, Shenyang, People's Republic of China.
Asia Pac J Public Health. 2021 Jan;33(1):39-45. doi: 10.1177/1010539520955088. Epub 2020 Sep 15.
The purpose of our study was to explore the association of blood pressure (BP) changes on short-and long-term outcomes of major adverse cardiovascular events (MACEs) in rural China. This study was designed to learn the effects of BP changes (2004-2008) on short-term (2008-2010, within 2 years of the initial examination) and long-term (2008-2017) outcomes of MACE, including 24 285 and 27 290 participants, respectively. In this study, 423 (short-term) and 1952 (long-term) MACEs were identified. For prehypertension to hypertension, the risk of long-term stroke was increased (hazard ratio [HR] = 1.18 [1.00-1.39]). For hypertension to prehypertension, the short-term MACE risk (0.65 [0.47-0.90]), short-term stroke risk (0.45 [0.26-0.76]), and long-term stroke risk (0.83 [0.70-0.99]) all decreased. Short-term outcomes conferred a stronger impact than long-term outcomes (Fisher test, measured as the difference of β coefficients, all < .05).
本研究旨在探讨中国农村人群血压(BP)变化与主要不良心血管事件(MACE)短期和长期结局的相关性。该研究旨在探讨 BP 变化(2004-2008 年)对 MACE 短期(2008-2010 年,初始检查后 2 年内)和长期(2008-2017 年)结局的影响,分别纳入了 24285 和 27290 名参与者。在本研究中,分别确定了 423 例(短期)和 1952 例(长期)MACE。对于从正常高值血压到高血压,长期中风风险增加(风险比[HR] = 1.18[1.00-1.39])。对于高血压到正常高值血压,短期 MACE 风险(0.65[0.47-0.90])、短期中风风险(0.45[0.26-0.76])和长期中风风险(0.83[0.70-0.99])均降低。短期结局的影响强于长期结局(Fisher 检验,β系数差异的测量值,均<0.05)。