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[胸腺瘤及相关疾病。关于255例接受手术治疗的胸腺瘤系列病例]

[Thymomas and associated diseases. Apropos of a series of 255 surgically treated thymomas].

作者信息

Levasseur P, Menestrier M, Gaud C, Dartevelle P, Julia P, Rojas-Miranda A, Navajas M, Le Brigand H, Merlier M

机构信息

Service de Chirurgie Thoracique, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson.

出版信息

Rev Mal Respir. 1988;5(2):173-8.

PMID:3293128
Abstract

The authors report on a series of 255 thymomas and the associated diseases most often auto-immune, myasthenia is the disease most frequently encountered (61% of cases). Next, but with a much reduced frequency of around 2%, come other diseases such as hypogammaglobulinaemia, erythroblastopenic anaemia, and disseminated lupus erythematosis. The authors analyse the effect of ablating the thymoma on the associated disease; those with myasthenia are the principal beneficiaries of thymic ablation, 83% in this series experiencing a good response. Besides myasthenia only erythroblastopenic anaemia obtained some benefit from thymic ablation; in all the other cases surgery to the thymic tumour had no benefit on the associated disease. In the light of their own experience the authors made a review of the literature of the different diseases associated with thymomas and made the point of the efficacy of thymectomy in the different diseases.

摘要

作者报告了一系列255例胸腺瘤及与之相关的疾病,这些相关疾病大多为自身免疫性疾病,其中重症肌无力是最常遇到的疾病(占病例的61%)。其次,但发生率低得多,约为2%的是其他疾病,如低丙种球蛋白血症、红细胞生成性贫血和播散性红斑狼疮。作者分析了切除胸腺瘤对相关疾病的影响;重症肌无力患者是胸腺切除的主要受益者,在本系列中83%的患者反应良好。除了重症肌无力,只有红细胞生成性贫血从胸腺切除中获得了一些益处;在所有其他病例中,胸腺肿瘤手术对相关疾病没有益处。根据他们自己的经验,作者回顾了与胸腺瘤相关的不同疾病的文献,并指出了胸腺切除术在不同疾病中的疗效。

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