Opt Lett. 2020 Sep 15;45(18):4992-4995. doi: 10.1364/OL.400733.
Photo-plethysmography (PPG) making use of a monochromic light source and a photoelectric sensor is a non-invasive detection method to record blood volume changes in vessels and can be used to extract cardiac-related heart pulse information. Here, we demonstrated the fabrication of a monolithic photonic chip by integrating light-emitting diodes (LEDs) with photodetectors (PDs) on the same GaN-on-sapphire wafer containing InGaN/GaN multi-quantum wells (MQWs). The MQWs simultaneously act as light emitters in the LEDs and detectors in the PDs, and their mechanism has been studied. The fabricated chip operating in reflection mode is flip-chip bonded on a flexible polydimethylsiloxane (PDMS) strip, enabling the sapphire surface in close contact with the skin. The optical and electrical properties of the LED and PD have been thoroughly characterized, confirming that the PDs using identical MQWs can detect the reflected light from the LEDs. By attaching the chip to the wrist, PPG heart pulse signals from the arterial blood flow can be obtained, thereby verifying the feasibility of the proposed monolithic chip.
光体积描记法(PPG)利用单色光源和光电传感器,是一种非侵入式的检测方法,用于记录血管中的血量变化,并可用于提取与心脏相关的脉搏信息。在这里,我们展示了一种通过在同一个包含 InGaN/GaN 多量子阱(MQWs)的 GaN 蓝宝石晶圆上集成发光二极管(LED)和光电探测器(PD),制造出单片光子芯片的方法。MQWs 同时充当 LED 的发光体和 PD 的探测器,其工作机制已经过研究。工作在反射模式下的制造芯片被倒装芯片键合到柔性聚二甲基硅氧烷(PDMS)条上,使蓝宝石表面与皮肤紧密接触。对 LED 和 PD 的光电特性进行了彻底的表征,证实了使用相同 MQWs 的 PD 可以检测到来自 LED 的反射光。通过将芯片贴在手腕上,可以获得来自动脉血流的 PPG 脉搏信号,从而验证了所提出的单片芯片的可行性。