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腹腔镜子宫肌瘤剔除术后使用倒刺缝线与非倒刺缝线的生育结局比较。

Comparison of fertility outcomes after laparoscopic myomectomy for barbed versus nonbarbed sutures.

机构信息

Gynaecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Bologna, Italy.

Gynaecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), S. Orsola Hospital, University of Bologna, Bologna, Italy.

出版信息

Fertil Steril. 2021 Jan;115(1):248-255. doi: 10.1016/j.fertnstert.2020.07.036. Epub 2020 Sep 12.

Abstract

OBJECTIVE

To assess the impact on women's reproductive outcomes of barbed sutures to repair uterine breaches during laparoscopic myomectomy compared with traditional smooth sutures.

DESIGN

Retrospective, monocentric cohort study, with information on subsequent pregnancies prospectively acquired for some women.

SETTING

Tertiary-level academic referral center.

PATIENT(S): Women older than 18 years who had undergone a laparoscopic myomectomy and had sought pregnancy afterward, divided into two groups based on type of suture used to repair the uterine wall: group A (nonbarbed) and group B (barbed).

INTERVENTION(S): Laparoscopic removal of FIGO types 3, 4, 5, and 6 uterine leiomyomas by use of either only barbed sutures or only traditional smooth sutures to reconstruct the uterine defect.

MAIN OUTCOME MEASURE(S): Pregnancy achievement rates, delivery modes, main pregnancy complications, perioperative complications for both kinds of suture, and the trend of the use of barbed sutures over time at our center.

RESULT(S): Of 164 patients included, 83 were in group A and 81 in group B. Ninety-one patients (55.5%) experienced at least one postoperative pregnancy, with no differences between the groups (group A 60.5%; group B 50.6%). Of the 103 recorded postoperative pregnancies, 70 (68%) resulted in live births, 29 (28.1%) in first-trimester miscarriages, and 4 (3.9%) were ongoing.

CONCLUSION(S): Barbed sutures have a similar impact on reproductive outcomes as smooth conventional threads, both in terms of pregnancy and obstetric complication rates, after laparoscopic myomectomy.

摘要

目的

评估在腹腔镜子宫肌瘤剔除术中使用带刺缝线修复子宫破裂对女性生殖结局的影响,与传统的光滑缝线相比。

设计

回顾性、单中心队列研究,部分女性前瞻性获取随后妊娠的信息。

地点

三级学术转诊中心。

患者

年龄大于 18 岁的女性,行腹腔镜子宫肌瘤剔除术,并在术后寻求妊娠,根据用于修复子宫壁的缝线类型分为两组:A 组(非带刺)和 B 组(带刺)。

干预

通过使用仅带刺缝线或仅传统光滑缝线修复子宫缺陷,腹腔镜切除 FIGO 3、4、5 和 6 型子宫肌瘤。

主要观察指标

妊娠成功率、分娩方式、主要妊娠并发症、两种缝线的围手术期并发症,以及我们中心带刺缝线使用的趋势。

结果

164 例患者中,83 例在 A 组,81 例在 B 组。91 例(55.5%)至少经历了一次术后妊娠,两组之间无差异(A 组 60.5%;B 组 50.6%)。在记录的 103 例术后妊娠中,70 例(68%)足月分娩,29 例(28.1%)早期流产,4 例(3.9%)仍在继续。

结论

在腹腔镜子宫肌瘤剔除术中,与传统的光滑缝线相比,带刺缝线对生殖结局的影响相似,无论是在妊娠率还是产科并发症率方面。

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