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发作性睡病的当前药物治疗

Current pharmacologic management of narcolepsy.

作者信息

Scharf M B, Fletcher K A, Jennings S W

机构信息

Sleep Disorders Center, Mercy Hospital, Hamilton/Fairfield, Cincinnati, Ohio.

出版信息

Am Fam Physician. 1988 Jul;38(1):143-8.

PMID:3293383
Abstract

Narcolepsy is an incurable sleep disorder characterized by attacks of sleepiness and a series of auxiliary symptoms: cataplexy, sleep paralysis and hypnagogic hallucinations. Classic treatment has included stimulants to control sleepiness and tricyclic antidepressants to control the auxiliary symptoms. Polysomnography is necessary to confirm the diagnosis and to detect other sleep disorders. Recent developments in treatment include the use of codeine for sleepiness and gamma-hydroxybutyrate for auxiliary symptoms.

摘要

发作性睡病是一种无法治愈的睡眠障碍,其特征为嗜睡发作以及一系列辅助症状:猝倒、睡眠瘫痪和入睡幻觉。传统治疗方法包括使用兴奋剂来控制嗜睡,使用三环类抗抑郁药来控制辅助症状。多导睡眠图对于确诊和检测其他睡眠障碍是必要的。治疗方面的最新进展包括使用可待因治疗嗜睡,使用γ-羟基丁酸治疗辅助症状。

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