Universidade Federal de Mato Grosso do Sul, Programa de Pós-Graduação em Doenças Infecciosas e Parasitárias, Campo Grande, MS, Brasil.
Universidade Federal de Mato Grosso do Sul, Programa de Residência em Enfermagem Obstétrica, Campo Grande, MS, Brasil.
Rev Soc Bras Med Trop. 2020 Sep 11;53:e20200024. doi: 10.1590/0037-8682-0024-2020. eCollection 2020.
Syphilis is a sexually transmitted infection caused by Treponema pallidum. Considering the high rates of syphilis in pregnancy and congenital syphilis reported in Brazil in the past, and their serious consequences, this study described the epidemiological and clinical profile of pregnant women with a confirmed diagnosis of syphilis in Campo Grande, in the state of Mato Grosso do Sul, Brazil, from 2011 to 2017.
This is a descriptive study, based on syphilis notifications among pregnant women reported to the Sistema de Informação de Agravos de Notificação (National System of Disease Notification of Brazil).
Over the study period, 2,056 confirmed cases of syphilis in pregnancy were reported, resulting in a crude cumulative incidence of 144.76 cases per 1,000 live-born babies. The incidence increased from 9.97 cases per 1,000 live-born babies in 2011 to 36.10 cases per 1,000 live-born babies in 2017. It was more prevalent in women who were young, of mixed race, with low educational attainment. Over one third of women were diagnosed in the first trimester of pregnancy; therefore, they were at risk of reinfection if they or their sexual partners were inadequately treated. Furthermore, syphilis was not well classified according to its clinical stage, which led to inappropriate treatments.
Despite efforts to reduce the incidence of syphilis, syphilis during pregnancy remains a public health problem, reflecting possible inadequacies in antenatal care, especially in vulnerable populations. It is important to include sexual partners in syphilis treatment during pregnancy to prevent reinfection.
梅毒是一种由苍白密螺旋体引起的性传播感染。考虑到巴西过去报告的妊娠梅毒和先天性梅毒的高发病率及其严重后果，本研究描述了 2011 年至 2017 年巴西南马托格罗索州坎波格兰德确诊妊娠梅毒孕妇的流行病学和临床特征。
这是一项基于向国家疾病报告系统（巴西全国疾病报告系统）报告的妊娠梅毒病例的描述性研究。
在研究期间，报告了 2056 例确诊的妊娠梅毒病例，粗累积发病率为每 1000 例活产婴儿 144.76 例。发病率从 2011 年的每 1000 例活产婴儿 9.97 例上升到 2017 年的每 1000 例活产婴儿 36.10 例。该病在年轻、混血、教育程度低的女性中更为普遍。超过三分之一的女性在妊娠早期被诊断出来；因此，如果她们或其性伴侣治疗不当，她们有再次感染的风险。此外，梅毒的临床分期分类不当，导致治疗不当。
尽管努力降低梅毒的发病率，但妊娠梅毒仍然是一个公共卫生问题，反映出可能在产前保健方面存在不足，尤其是在弱势群体中。在妊娠期间治疗梅毒时将性伴侣包括在内，以防止再次感染非常重要。
