Witkovsky P, Stone S, Besharse J C
Department of Ophthalmology, New York University Medical Center, NY 10016.
Brain Res. 1988 May 24;449(1-2):332-6. doi: 10.1016/0006-8993(88)91048-7.
Dopamine (greater than or equal to 2 microM) increased the cone input and suppressed the rod input to axon-bearing horizontal cells of the Xenopus retina. Dopamine (10 microM) also depolarized the horizontal cell by about 9 mV. The D2-dopamine antagonists spiperone and metoclopramide had the opposite action to dopamine, whereas the D1-dopamine antagonist SCH 23390 was without effect. None of the agents tested modified the light-evoked responses of rods.
多巴胺（大于或等于2微摩尔）增加了非洲爪蟾视网膜中向轴突水平细胞的视锥细胞输入，并抑制了视杆细胞输入。多巴胺（10微摩尔）还使水平细胞去极化约9毫伏。D2多巴胺拮抗剂螺哌隆和甲氧氯普胺的作用与多巴胺相反，而D1多巴胺拮抗剂SCH 23390则没有效果。所测试的药物均未改变视杆细胞的光诱发反应。
