Taylor James Kyle, Carpio-Rivera Elizabeth, Chacón-Araya Yamileth, Grandjean Peter W, Moncada-Jiménez José
Auburn University at Montgomery.
University of Costa Rica.
Res Q Exerc Sport. 2022 Mar;93(1):130-143. doi: 10.1080/02701367.2020.1812493. Epub 2020 Sep 17.
: To determine the acute and chronic effects of exercise on Paraoxonase-1 (PON1) concentration and activity. : A literature search was performed using 16 electronic databases. Effect sizes (ES) were computed and two-tailed α values < .05 and non-overlapping 95% confidence intervals (95%CI) were considered statistically significant. Heterogeneity, inconsistency (), and small-study effects using the LFK index were examined. : Eighteen studies ( = 377 participants) met the criteria for inclusion. The acute effects of exercise on PON1 concentration were trivial and non-significant (ES = -.03, 95%CI = -.39 to .34, > .05), heterogeneous ( = .05), moderately inconsistent ( = 48%), with minor asymmetry (LFK index = 1.34). The chronic effects of exercise on PON1 concentration were also trivial and non-significant (ES = -.04, 95%CI = -.53 to.45, > .05), homogenous ( = .65), displayed low inconsistency ( = 0%), and minor asymmetry (LFK index = -1.14). The acute effects of exercise on PON1 activity were trivial and non-significant (ES = .11, 95%CI = -.02 to.24, > .05), homogenous ( = .85), showed low inconsistency ( = 0%), and no asymmetry (LFK index = .82). The chronic effects of exercise on PON1 activity were trivial and non-significant (ES = .31, 95%CI = -.03 to.65, > .05), homogenous ( = .17), moderately inconsistent ( = 36%), with no asymmetry (LFK index = .60). : Acute and chronic exercise training, overall, exerted a trivial effect on PON1 concentration and activity.
确定运动对对氧磷酶-1（PON1）浓度和活性的急性和慢性影响。
使用16个电子数据库进行文献检索。计算效应量（ES），双侧α值<0.05且95%置信区间（95%CI）不重叠被认为具有统计学意义。使用LFK指数检查异质性、不一致性（I²）和小研究效应。
18项研究（n = 377名参与者）符合纳入标准。运动对PON1浓度的急性影响微不足道且无统计学意义（ES = -0.03，95%CI = -0.39至0.34，P>0.05），具有异质性（I² = 0.05），中度不一致（I² = 48%），存在轻微不对称（LFK指数 = 1.34）。运动对PON1浓度的慢性影响同样微不足道且无统计学意义（ES = -0.04，95%CI = -0.53至0.45，P>0.05），具有同质性（I² = 0.65），显示出低不一致性（I² = 0%），以及轻微不对称（LFK指数 = -1.14）。运动对PON1活性的急性影响微不足道且无统计学意义（ES = 0.11，95%CI = -0.02至0.24，P>0.05），具有同质性（I² = 0.85），显示出低不一致性（I² = 0%），且无不对称（LFK指数 = 0.82）。运动对PON1活性的慢性影响微不足道且无统计学意义（ES = 0.31，95%CI = -0.03至0.65，P>0.05），具有同质性（I² = 0.17），中度不一致（I² = 36%），无不对称（LFK指数 = 0.60）。
总体而言，急性和慢性运动训练对PON1浓度和活性的影响微不足道。
