Daamen Lois A, Heerkens Hanne D, Molenaar I Q Quintus, Verkooijen H Lenny M, Meijer Gert J, Intven Martijn P W
UMCU, Utrecht. Afd. Radiotherapie.
Contact: Lois A. Daamen (
Ned Tijdschr Geneeskd. 2020 Aug 13;164:D4780.
MRI-guided radiotherapy is a new technique for high-precision radiation(stereotactic radiotherapy) for patients with malignancies. This minimally invasive treatmentis carried out with the aid of an irradiation device with an integrated MRI scanner, the 'magnetic resonance linear accelerator' (MR-Linac), which is used to image the tumour and surrounding tissue immediately before each radiotherapy treatment. The radiation plan can be adapted on the basis of the latest MRI image as required. MRI-guided radiotherapy can have advantages when treating patients with malignancies in the upper abdomen, such as pancreatic carcinoma or periampullary malignancies. These tumours and the surrounding tissues are often poorly visible on the CT scans used in conventional radiotherapy techniques. Patients with upper-abdominal malignancies can be precisely and effectively treated with MRI-guided radiotherapy and organs that are sensitive to radiation can be spared as much as possible, thus decreasing the risk of side-effects.
磁共振成像引导放疗是一种用于恶性肿瘤患者的高精度放疗新技术(立体定向放疗)。这种微创治疗借助于一种集成了磁共振成像扫描仪的放疗设备,即“磁共振直线加速器”(MR-Linac)来进行,该设备用于在每次放疗前即刻对肿瘤及周围组织进行成像。放疗计划可根据最新的磁共振成像按需调整。在治疗上腹部恶性肿瘤患者时,如胰腺癌或壶腹周围恶性肿瘤,磁共振成像引导放疗可能具有优势。在传统放疗技术所使用的CT扫描中,这些肿瘤及其周围组织往往显示不清。上腹部恶性肿瘤患者可通过磁共振成像引导放疗得到精确有效的治疗,并且对辐射敏感的器官可尽可能得到保护,从而降低副作用风险。