Marsh Rachel L, Spohn Gina P, Kaffenberger Jessica A
Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
Dermatol Online J. 2020 Aug 15;26(8):13030/qt8ks9j8sv.
Erosive pustular dermatosis of the scalp (EPDS) is a rare inflammatory condition commonly associated with antecedent iatrogenic insult. EPDS may be diagnostically challenging owing to a lack of pathognomonic histologic findings and cutaneous manifestations that overlap with alternative dermatologic conditions. Therefore, EPDS may be more common than previously recognized. We present a 60-year-old woman with a four-year history of non-healing scalp erosions, progressive skin atrophy, and scarring alopecia despite intravenous antibiotics and intraoperative debridement who improved with systemic glucocorticoids. Our report emphasizes the importance of early recognition of EPDS when delayed wound healing and erosive disease occur in the setting of iatrogenic injury to the scalp. Timely treatment with systemic anti-inflammatory agents is paramount to prevent cicatricial alopecia and mitigate further scalp insult in EPDS.
头皮糜烂性脓疱性皮肤病（EPDS）是一种罕见的炎症性疾病，通常与先前的医源性损伤有关。由于缺乏特征性的组织学表现以及与其他皮肤病重叠的皮肤表现，EPDS的诊断可能具有挑战性。因此，EPDS可能比以前认为的更为常见。我们报告了一名60岁女性，尽管接受了静脉抗生素治疗和术中清创术，但头皮糜烂不愈合、皮肤进行性萎缩和瘢痕性脱发已有四年病史，经全身糖皮质激素治疗后病情改善。我们的报告强调了在头皮医源性损伤的情况下出现伤口愈合延迟和糜烂性疾病时，早期识别EPDS的重要性。及时使用全身抗炎药治疗对于预防EPDS中的瘢痕性脱发和减轻进一步的头皮损伤至关重要。
