Din Ryan S, Tsiaras William G, Mostaghimi Arash
Brigham and Women's Hospital, Boston, MA.
Wounds. 2018 Aug;30(8):E84-E86.
Erosive pustular dermatosis of the scalp (EPDS) is a noninfectious inflammatory disorder characterized by pustules, erosions, ulcerations, and crusted erythematous plaques that is often associated with mechanical or chemical trauma. While its appearance may mimic infection, its etiology is thought to have an autoimmune component based on responsiveness to immunomodulators.
Herein, the authors present 2 cases of EPDS that were initially treated as primary infections. In both cases, the wounds did not respond to antimicrobial treatment and led to severe ulceration, exposing cranial bone. Both wounds improved with topical corticosteroid therapy.
These cases represent the importance of considering topical steroid treatment and a diagnosis of EPDS after debridement for purulent scalp ulcers.
头皮糜烂性脓疱病(EPDS)是一种非感染性炎症性疾病,其特征为脓疱、糜烂、溃疡以及结痂的红斑性斑块,常与机械性或化学性创伤相关。虽然其外观可能类似感染,但基于对免疫调节剂的反应,其病因被认为具有自身免疫成分。
在此,作者介绍2例最初被当作原发性感染治疗的EPDS病例。在这两个病例中,伤口对抗菌治疗均无反应,并导致严重溃疡,颅骨外露。两个伤口经外用皮质类固醇治疗后均有改善。
这些病例表明,对于化脓性头皮溃疡进行清创后,考虑外用类固醇治疗及EPDS诊断具有重要意义。