Wong P, Mason E O, Barrett F F
South Med J. 1977 Aug;70(8):978-9. doi: 10.1097/00007611-197708000-00023.
Control of nosocomial group B streptococcal (GBS) colonization of newborn infants was attempted in a four-cycle study alternately employing single applications of povidone-iodine (iodophor) and triple dye to the umbilical cord stump and periumbilical area. GBS colonization rates were 49% and 34% following iodophor cord care (cycles II and III) and 11% and 50% following triple dye cord care (cycles II and IV). The apparent significant reduction of GBS colonization during triple dye cycle II could not be reproduced in a subsequent follow-up culture survey and remains unexplained.
在一项为期四个周期的研究中,尝试通过交替对新生儿脐带残端和脐周区域单次应用聚维酮碘(碘伏)和三联染料来控制医院内B族链球菌(GBS)对新生儿的定植。在使用碘伏进行脐带护理后(第二和第三周期),GBS定植率分别为49%和34%;在使用三联染料进行脐带护理后(第二和第四周期),GBS定植率分别为11%和50%。在三联染料第二周期期间GBS定植明显显著降低,但在随后的随访培养调查中未能重现,原因不明。