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[Venetoclax combined with azacitidine in the treatment of elderly patients with acute myeloid leukemia or myeloid sarcoma: Three cases reports and literature review].

作者信息

Tian F Q, Zhang L S, Li J H, Tang M Q, Jiang J, Cheng X H, Zhang X C, Jiang M

机构信息

Department of Hematology, Longgang District People's Hospital of Shenzhen, Shenzhen 518172, China.

Department of Hematology, Lanzhou University Second Hospital, Lanzhou 730030, China.

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2020 Aug 14;41(8):694-696. doi: 10.3760/cma.j.issn.0253-2727.2020.08.016.

DOI:10.3760/cma.j.issn.0253-2727.2020.08.016
PMID:32942828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7525173/
Abstract
摘要

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本文引用的文献

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Outcomes of older patients with NPM1-mutated AML: current treatments and the promise of venetoclax-based regimens.NPM1 突变型 AML 老年患者的预后：现有治疗方法和 Venetoclax 为基础的方案的前景。
Blood Adv. 2020 Apr 14;4(7):1311-1320. doi: 10.1182/bloodadvances.2019001267.
2
Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study.维奈克拉联合阿糖胞苷和/或伊达比星治疗复发/难治性儿童急性髓系白血病的 1 期、剂量递增研究。
Lancet Oncol. 2020 Apr;21(4):551-560. doi: 10.1016/S1470-2045(20)30060-7. Epub 2020 Mar 11.
3
Defining Acute Myeloid Leukemia Ontogeny in Older Patients.定义老年患者急性髓系白血病的发生机制。
Clin Lymphoma Myeloma Leuk. 2020 May;20(5):312-315. doi: 10.1016/j.clml.2019.11.007. Epub 2019 Nov 9.
4
How we use venetoclax with hypomethylating agents for the treatment of newly diagnosed patients with acute myeloid leukemia.我们如何将维奈托克与低甲基化剂联合用于治疗新诊断的急性髓系白血病患者。
Leukemia. 2019 Dec;33(12):2795-2804. doi: 10.1038/s41375-019-0612-8. Epub 2019 Oct 18.
5
MCL-1 inhibitors - where are we now (2019)?MCL-1 抑制剂——我们现在在哪里（2019 年）？
Expert Opin Ther Pat. 2019 Nov;29(11):909-919. doi: 10.1080/13543776.2019.1672661. Epub 2019 Oct 14.
6
MicroRNA-497 inhibits multiple myeloma growth and increases susceptibility to bortezomib by targeting Bcl-2.MicroRNA-497 通过靶向 Bcl-2 抑制多发性骨髓瘤的生长并增加硼替佐米的敏感性。
Int J Mol Med. 2019 Feb;43(2):1058-1066. doi: 10.3892/ijmm.2018.4019. Epub 2018 Dec 7.
7
Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia.维奈托克联合地西他滨或阿扎胞苷治疗初治老年急性髓系白血病患者。
Blood. 2019 Jan 3;133(1):7-17. doi: 10.1182/blood-2018-08-868752. Epub 2018 Oct 25.
8
Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study.在未经治疗的老年急性髓系白血病患者中，venetoclax 联合地西他滨或阿扎胞苷的安全性和初步疗效：一项非随机、开放标签、1b 期研究。
Lancet Oncol. 2018 Feb;19(2):216-228. doi: 10.1016/S1470-2045(18)30010-X. Epub 2018 Jan 12.
9
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Blood. 2015 Jul 16;126(3):291-9. doi: 10.1182/blood-2015-01-621664. Epub 2015 May 18.