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Correlation between hemoglobin A1c and serum lipid profile in Afghani patients with type 2 diabetes: hemoglobin A1c prognosticates dyslipidemia.阿富汗2型糖尿病患者糖化血红蛋白与血脂谱的相关性:糖化血红蛋白可预测血脂异常。
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Cardiovasc J Afr. 2015 Jul-Aug;26(4):188-92. doi: 10.5830/CVJA-2015-050.
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尼泊尔东部一家三级护理中心对2型糖尿病患者美国糖尿病协会(ADA)目标达成情况的评估。

Assessment of Achievement of American Diabetes Association (ADA) Targets in Patients with Type 2 Diabetes Mellitus at a Tertiary Care Centre in Eastern Nepal.

作者信息

Baranwal Jouslin K, Maskey Robin, Chaudhari Rajendra K, Sherchand Ojaswee

机构信息

Department of Biochemistry, B.P Koirala Institute of Health Sciences, Dharan, Nepal.

Department of Internal Medicine, B.P Koirala Institute of Health Sciences, Dharan, Nepal.

出版信息

Diabetes Metab Syndr Obes. 2020 Aug 21;13:2959-2964. doi: 10.2147/DMSO.S262643. eCollection 2020.

DOI:10.2147/DMSO.S262643
PMID:32943892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7468501/
Abstract

BACKGROUND

Management of type 2 diabetes is not limited to blood glucose control, it also addresses blood pressure and lipid levels in order to prevent associated vascular complications and improve the chances of survival and quality-of-life. Although the American Diabetes Association (ADA) has lain specific target levels for glycated hemoglobin, blood pressure and serum low density cholesterol to be achieved by non-pregnant patients with type 2 diabetes mellitus, these are not being achieved in practice. We took on this study to describe the extent of ADA target achievement at our center.

METHODS

We analyzed data of type 2 diabetes patients who attended the endocrinology clinic at our hospital within the past 1 year from the start of the study. Data of the pregnant women and patients with mentions of conditions that might interfere with measurement of HbA1c were excluded.

RESULTS

We analyzed 336 records, 45.8% (n=154) males and 54.16% (n=182) females. The mean age of patients was 52.28±11.9 years. The percentages of patients who had HbA1c <7%, blood pressure <140/90 mm of Hg, and LDL-c <100 mg/dL were 56.5%, 72%, and 56.3%, respectively. Only 37.8% of patients were found to have achieved all three ADA targets. Our findings show that a higher percentage of patients who were ≥50 years of age met LDL-c goals as compared to those <50 years of age, 61.9% vs 49% (<0.05) and that blood pressure control was better among younger age group, 78.9% vs 66.7% (<0.05).

CONCLUSION

Our study highlights that a significant proportion of patients missed on achieving the ADA targets. This is worrisome and further studies should be done to find out possible reasons behind this.

摘要

背景

2型糖尿病的管理不仅限于血糖控制,还涉及血压和血脂水平,以预防相关血管并发症并提高生存几率和生活质量。尽管美国糖尿病协会(ADA)为非妊娠2型糖尿病患者设定了糖化血红蛋白、血压和血清低密度胆固醇的具体目标水平,但在实际中这些目标并未实现。我们开展这项研究以描述我们中心达到ADA目标的程度。

方法

我们分析了自研究开始起过去1年内到我院内分泌门诊就诊的2型糖尿病患者的数据。排除了孕妇以及提及可能干扰糖化血红蛋白测量的疾病的患者的数据。

结果

我们分析了336份记录,男性占45.8%(n = 154),女性占54.16%(n = 182)。患者的平均年龄为52.28±11.9岁。糖化血红蛋白<7%、血压<140/90 mmHg以及低密度脂蛋白胆固醇<100 mg/dL的患者百分比分别为56.5%、72%和56.3%。仅37.8%的患者被发现达到了所有三项ADA目标。我们的研究结果表明,与年龄<50岁的患者相比,年龄≥50岁的患者达到低密度脂蛋白胆固醇目标的比例更高,分别为61.9%和49%(P<0.05),并且较年轻年龄组的血压控制更好,分别为78.9%和66.7%(P<0.05)。

结论

我们的研究强调,很大一部分患者未达到ADA目标。这令人担忧,应进一步开展研究以找出其背后可能的原因。