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回复 A. Bianchi 和 M. Savastano 的《Chem. Commun., 2020, 56, D0CC01189D》中的“Comment on "Investigation of Zr(iv) and Zr(iv) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging""》。

Reply to the 'Comment on "Investigation of Zr(iv) and Zr(iv) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging"' by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D.

机构信息

Université de Nantes, CNRS, Inserm, CRCINA, F-44000 Nantes, France.

Center for Molecular Modeling, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Chem Commun (Camb). 2020 Oct 25;56(83):12667-12668. doi: 10.1039/d0cc03594g. Epub 2020 Sep 18.

Abstract

The alternative analysis of A. Bianchi and M. Savastano is a valuable contribution to the understanding of the complex systems at stake in the complexation chemistry of Zr by considering polynuclear species. Placed in the context of nuclear medicine where such aggregates are unlikely and considering recent literature data, this however points out that no clear agreement exists to describe such complex formation.

摘要

A. Bianchi 和 M. Savastano 的另类分析通过考虑多核物种,对理解Zr 配合物化学中所涉及的复杂系统做出了有价值的贡献。考虑到此类聚集体在核医学中不太可能出现,并且考虑到最近的文献数据,这表明目前还没有明确的共识来描述这种复杂的形成。

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