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犬白内障超声乳化术后青光眼与术前房角镜状态的相关性:505 只眼回顾性队列研究。

Association between preoperative gonioscopic status and postoperative glaucoma after phacoemulsification in dogs: A retrospective cohort study of 505 eyes.

机构信息

Animal Eye Care, East Malvern, Vic, Australia.

Jemora Pty Ltd, Geelong, Vic, Australia.

出版信息

Vet Ophthalmol. 2021 Mar;24 Suppl 1:39-49. doi: 10.1111/vop.12818. Epub 2020 Sep 18.

Abstract

OBJECTIVE

To assess whether preoperative gonioscopy status is associated with the development of postoperative glaucoma after phacoemulsification.

PROCEDURE

Eligible dogs and eyes were selected from medical records (2007-2017), and each eye was classified as having normal or abnormal gonioscopy status. Records were examined for postoperative glaucoma, and data were collected for baseline variables including patient signalment, surgical factors, and pre, intra, and postoperative medications.

RESULTS

Of 305 dogs (505 eyes) selected for review in this study, 111 dogs (163 eyes) had abnormal gonioscopy findings, and 194 dogs (342 eyes) had normal gonioscopy findings. Postoperative glaucoma occurred in 24% (39/163) of eyes with abnormal gonioscopy and in 14% (49/342) eyes with normal gonioscopy. Eyes with abnormal gonioscopy status were at higher risk of postoperative glaucoma compared to normal eyes (P = .025). There was no important confounding due to the numerous baseline variables summarised above. Regardless of gonioscopy status, the risk of glaucoma was highest during the first 2 months after surgery.

CONCLUSIONS

Eyes with abnormal gonioscopy findings are at increased risk of postoperative glaucoma compared with eyes with normal gonioscopy findings. Gonioscopy is recommended as a part of presurgical assessment in all dogs prior to phacoemulsification. Further study is needed to assess whether the incidence of postoperative glaucoma can be reduced by increased monitoring or altered treatment protocols in cases that are known to have abnormal gonioscopy findings prior to cataract surgery.

摘要

目的

评估超声乳化术后青光眼的发生是否与术前房角状态有关。

方法

从病历中选择符合条件的犬和眼睛(2007-2017 年),每只眼分为房角镜检查正常或异常。检查术后青光眼,并收集基线变量的数据,包括患者特征、手术因素以及术前、术中、术后用药。

结果

在本研究中,对 305 只犬(505 只眼)进行了回顾性分析,111 只犬(163 只眼)存在异常房角镜检查结果,194 只犬(342 只眼)存在正常房角镜检查结果。异常房角镜检查的眼术后青光眼发生率为 24%(39/163),正常房角镜检查的眼为 14%(49/342)。与正常房角镜检查的眼相比,异常房角镜检查的眼发生术后青光眼的风险更高(P=0.025)。尽管存在上述大量的基线变量,但并未发生重要的混杂。无论房角镜状态如何,术后青光眼的风险在术后 2 个月内最高。

结论

与房角镜检查正常的眼相比,房角镜检查异常的眼发生术后青光眼的风险更高。建议在进行超声乳化术前对所有犬进行房角镜检查。需要进一步研究评估,在白内障手术前已知房角镜检查异常的情况下,通过增加监测或改变治疗方案是否可以降低术后青光眼的发生率。

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