建立鸟枪弹样脉络膜视网膜病变的健康效用值。
Creating a Health Utility Value for Birdshot Chorioretinopathy.
机构信息
Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
出版信息
Ocul Immunol Inflamm. 2022 Jan 2;30(1):73-80. doi: 10.1080/09273948.2020.1799034. Epub 2020 Sep 18.
PURPOSE
To create a health utility value for birdshot chorioretinopathy (BCR) using Time Trade-Off (TTO) and Standard Gamble (SG) utilities.
METHOD
Adult BCR patients completed TTO, SG, EQ-5D-5L, and NEI VFQ-25 questionnaires and underwent a detailed history and clinical examination.
RESULTS
A total of 28 BCR patients (9 M, 19 F; mean age 62 years, range 47-83) were included. There were 22 patients with a logMAR vision of 0.3 or better in both eyes. Mean TTO was 0.90 ± SD 0.18 (range 0.33-1.0) and mean SG was 0.94 ± SD 0.14 (range 0.5-1.0). TTO correlated with EQ-5D-5L index value ( = .024) and NEI VFQ-25 composite score ( = .015).
CONCLUSIONS
Of 28 patients with BCR, 11 would trade remaining life (mean 5.4 years), and 6 would take a risk of immediate death (mean 28% risk), in return for perfect vision in both eyes for the rest of their life.
目的
使用时间权衡（TTO）和标准博弈（SG）效用值为鸟枪弹样脉络膜视网膜病变（BCR）创建健康效用值。
方法
成年 BCR 患者完成 TTO、SG、EQ-5D-5L 和 NEI VFQ-25 问卷，并接受详细的病史和临床检查。
结果
共纳入 28 例 BCR 患者（9 例男性，19 例女性；平均年龄 62 岁，范围 47-83 岁）。有 22 例患者双眼的 logMAR 视力为 0.3 或更好。平均 TTO 为 0.90±0.18（范围 0.33-1.0），平均 SG 为 0.94±0.14（范围 0.5-1.0）。TTO 与 EQ-5D-5L 指数值（ =0.024）和 NEI VFQ-25 综合评分（ =0.015）相关。
结论
在 28 例 BCR 患者中，11 例患者愿意用余生（平均 5.4 年）来换取余生双眼的完美视力，6 例患者愿意冒立即死亡的风险（平均 28%的风险）。
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