Gebrie Alemu
Department of Biomedical Science, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Diabetes Metab Syndr. 2020 Sep-Oct;14(5):1551-1556. doi: 10.1016/j.dsx.2020.08.002. Epub 2020 Aug 13.
There is a growing concern about metabolic syndrome among HIV-infected patients. Therefore, this study aims to determine the burden of metabolic syndrome among patients living with HIV/AIDS at referral hospitals of Northwest Ethiopia.
a hospital-based cross-sectional study was conducted at referral hospitals of Northwest Ethiopia between February 2019 and April 2019. Using the WHO stepwise approach, sociodemographic, behavioral, and clinical data were collected from 407 adult patients. Lipid profiles, fasting blood sugar, as well as anthropometric indicators, were also measured. In addition, multivariate binary logistic regression analysis was performed.
The prevalence of metabolic syndrome was found to be 24.6% (95 CI: 20.42,28.78). Multivariate logistic regression analysis revealed that age [AOR (95% CI) 1.04 (1.003,1.074), p < 0.05]; female gender [AOR (95% CI) 9.66 (4.40, 21.22), p < 0.05]; marital status, single referent, separated [AOR (95% CI) 4.77 (1.83, 12.41), p < 0.05] and widowed [AOR (95% CI) 3.868(1.375, 10.883), p < 0.05]; monthly income (<2000 Ethiopian Birr referent) > 5000 ETB [AOR (95% CI) 3.543 (1.299, 9.664), p < 0.05]; and urban residence [AOR (95% CI) 2.118 (1.089, 4.119), p < 0.05] have shown statistically significant association with odds of metabolic syndrome.
The burden of metabolic syndrome was notably higher. Age, gender, marital status, monthly income, residence, waist circumference, and hypertension of patients were significantly associated with metabolic syndrome.
感染艾滋病毒的患者中,代谢综合征问题日益受到关注。因此,本研究旨在确定埃塞俄比亚西北部转诊医院中感染艾滋病毒/艾滋病患者的代谢综合征负担。
2019年2月至2019年4月,在埃塞俄比亚西北部的转诊医院开展了一项基于医院的横断面研究。采用世界卫生组织的逐步方法,收集了407名成年患者的社会人口统计学、行为学和临床数据。还测量了血脂谱、空腹血糖以及人体测量指标。此外,进行了多变量二元逻辑回归分析。
发现代谢综合征的患病率为24.6%(95%置信区间:20.42,28.78)。多变量逻辑回归分析显示,年龄[AOR(95%置信区间)1.04(1.003,1.074),p<0.05];女性[AOR(95%置信区间)9.66(4.40,21.22),p<0.05];婚姻状况,以单身为参照,分居[AOR(95%置信区间)4.77(1.83,12.41),p<0.05]和丧偶[AOR(95%置信区间)3.868(1.375,10.883),p<0.05];月收入(以<2000埃塞俄比亚比尔为参照)>5000埃塞俄比亚比尔[AOR(95%置信区间)3.543(1.299,9.664),p<0.05];以及城市居住[AOR(95%置信区间)2.118(1.089,4.119),p<0.05]与代谢综合征的患病几率存在统计学显著关联。
代谢综合征的负担明显更高。患者的年龄、性别、婚姻状况、月收入、居住地、腰围和高血压与代谢综合征显著相关。