Gallegos Jose E, Inglesby Dani C, Young Zachary T, Herrera Fernando A
College of Medicine, Medical University of South Carolina, Charleston, SC.
College of Medicine, Medical University of South Carolina, Charleston, SC; Division of Plastic and Reconstructive Surgery, Medical University of South Carolina, Charleston, SC.
J Hand Surg Am. 2021 Jan;46(1):54-59. doi: 10.1016/j.jhsa.2020.07.009. Epub 2020 Sep 16.
Raynaud phenomenon (RP) is a condition causing vasospasm in the fingers and toes of patients that can have a significant negative impact on quality of life. This can lead to pain, ulceration, and possible loss of digits. Several pharmacological options are available for treatment. However, RP can often be refractory to traditional modalities, leaving surgery or injections as the next available options. This article provides a review and update on the use of botulinum toxin as an effective therapy for the treatment of RP refractory to medical management.
雷诺现象（RP）是一种导致患者手指和脚趾血管痉挛的病症，会对生活质量产生重大负面影响。这可能会导致疼痛、溃疡，甚至可能导致手指丧失。有几种药物治疗选择。然而，RP通常对传统治疗方式难以奏效，使得手术或注射成为接下来可行的选择。本文对肉毒杆菌毒素作为治疗难治性RP的有效疗法的应用进行综述和更新。
