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口腔创伤学系统评价的证据图谱和质量评估。

Evidence mapping and quality assessment of systematic reviews in dental traumatology.

机构信息

Pedodontics & Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

Conservative Dentistry and Endodontics, Regional Institute of Medical Sciences, Imphal, India.

出版信息

Dent Traumatol. 2021 Feb;37(1):17-36. doi: 10.1111/edt.12606. Epub 2020 Oct 4.

Abstract

BACKGROUND/AIMS: Evidence mapping of systematic reviews (SRs) systematically and comprehensively identifies, organizes, and summarizes the distribution of scientific evidence in a field. The aims of this study were to delineate domains in dental traumatology (DT), evaluate the existing SRs within the domains, and identify the paucity of evidence for future research.

METHODS

Domains and sub-domains of DT were established according to the methods of qualitative research. The protocol for evidence mapping was prepared as per the guidelines of GEM and PRISMA. The search strategy was formulated using words and MeSH terms in eight databases without restriction of languages and year of publication. Gray literature, protocol registries, and references of selected articles were also searched. Duplicates were removed, and the final selection of SRs was completed. Data extraction and quality analysis using the ROBIS tool and the PRISMA checklist were performed.

RESULTS

The overall search resulted in 64 SRs from 1999 to 2020 with 44 published in last six years. The highest number of SRs had been performed in the Prognostic domain (n = 19) followed by the domains of Epidemiology (n = 15), Therapeutics (n = 10), Oral Biology (n = 7), Diagnostics (n = 6), Preventive (n = 5), and Research Methods (n = 2). Within each domain, there were variabilities in the number of reviewers, a priori protocols, search limitations, risk of bias methods, and meta-analysis. Of the SRs, including 4 Cochrane reviews, 28.4% were inconclusive. A low risk of bias was found in 48.4% of the SRs. Among the registered and ongoing SRs, six were from the domain of epidemiology, two in the domain of therapeutics, five from prognostics, and one each in the domains of prevention and research methods.

CONCLUSION

The SRs in DT could be mapped in seven domains with variabilities in the methods. The majority had an a priori registered protocol and a low risk of reporting errors. Within the Epidemiology and Preventive domains, SRs were present in all the sub-domains with the majority demonstrating low-risk of bias (ROB). The domain of prognosis had SRs in most sub-domains but with a high ROB. Insufficient numbers of SRs were present in most sub-domains of the Diagnostics, Therapeutics, Research Methods and Oral Biology domains.

摘要

背景/目的:系统评价证据图谱系统且全面地识别、组织和总结某一领域科学证据的分布。本研究的目的是划定牙外伤学(DT)领域,评估该领域内现有的系统评价,并确定未来研究证据的缺乏。

方法

根据定性研究方法确定 DT 的领域和子领域。证据图谱的方案按照 GEM 和 PRISMA 指南制定。检索策略是使用八个数据库中的单词和 MeSH 术语制定的,没有语言和发表年份的限制。还检索了灰色文献、方案注册处和选定文章的参考文献。删除重复项,并完成最终的系统评价选择。使用 ROBIS 工具和 PRISMA 检查表进行数据提取和质量分析。

结果

总体搜索结果为 1999 年至 2020 年的 64 项系统评价,其中 44 项发表于过去六年。发表数量最多的系统评价是在预后领域(n=19),其次是流行病学(n=15)、治疗学(n=10)、口腔生物学(n=7)、诊断学(n=6)、预防(n=5)和研究方法(n=2)。在每个领域内,审稿人数量、事先制定的方案、搜索限制、偏倚风险方法和荟萃分析均存在差异。在包括 4 项 Cochrane 评价的系统评价中,有 28.4%的结论不确定。48.4%的系统评价被认为低偏倚风险。在已注册和正在进行的系统评价中,有 6 项来自流行病学领域,2 项来自治疗学领域,5 项来自预后领域,1 项分别来自预防和研究方法领域。

结论

DT 的系统评价可以分为七个领域,方法存在差异。大多数系统评价都有事先注册的方案和低报告错误风险。在流行病学和预防领域,所有子领域都有系统评价,大多数系统评价的偏倚风险较低(ROB)。预后领域的大多数子领域都有系统评价,但 ROB 较高。诊断学、治疗学、研究方法和口腔生物学领域的大多数子领域的系统评价数量都不足。

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