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胰腺淋巴上皮囊肿:细针穿刺诊断的挑战。

Lymphoepithelial cyst of the pancreas: A challenging diagnosis on fine needle aspiration.

机构信息

Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA.

Department of Pathology, Mayo Clinic, Rochester, MN, USA.

出版信息

Ann Diagn Pathol. 2020 Dec;49:151603. doi: 10.1016/j.anndiagpath.2020.151603. Epub 2020 Aug 21.

Abstract

Lymphoepithelial cysts (LECs) of the pancreas are rare, benign pancreatic cysts comprising approximately 0.5% of all pancreatic cysts. They occur predominantly in men in the 5th and 6th decades of life. LECs are true cysts lined by stratified squamous epithelium with adjacent subepithelial lymphoid tissue. They range in size from 1.2 to 17 cm (mean size 4.6 cm) and can arise in any part of the pancreas. 1 LEC resembles other benign and malignant pancreatic cysts clinically and radiologically. The cytomorphologic features of LECs have been described in a small number of case reports and it has been indicated that features may overlap with other benign and malignant pancreatic lesions. Herein, we report clinical, radiological, cytological and histopathological features of a pancreatic LEC in a 62-year-old male.

摘要

胰腺淋巴上皮囊肿(Lymphoepithelial Cysts,LECs)罕见,是一种良性胰腺囊肿,约占所有胰腺囊肿的 0.5%。它们主要发生在 50 至 60 岁的男性中。LEC 是由复层鳞状上皮衬里的真正囊肿,伴有相邻的上皮下淋巴组织。它们的大小从 1.2 厘米到 17 厘米不等(平均大小为 4.6 厘米),可以发生在胰腺的任何部位。1 LEC 在临床上和影像学上与其他良性和恶性胰腺囊肿相似。少数病例报告描述了 LEC 的细胞形态学特征,并表明其特征可能与其他良性和恶性胰腺病变重叠。在此,我们报告了一位 62 岁男性胰腺 LEC 的临床、放射学、细胞学和组织病理学特征。

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